CAJ | 학술논문

目的：探讨双相障碍躁狂相、抑郁相与性腺激素的关系。方法选取诊断符合国际疾病分类诊断标准的双相情感障碍躁狂发作患者30例和双相情感障碍抑郁发作患者30例，入组后及治疗1个月后检测性腺激素（6项）。结果双相躁狂组男性患者治疗前血清睾酮水平显著高于治疗后及健康对照组睾酮水平，双相抑郁组患者治疗前血清雌二醇（E2）水平显著低于治疗后血清 E2水平及健康对照组 E2水平。结论睾酮与双相躁狂男性患者相关，E2与双相抑郁患者相关。
목적：탐토쌍상장애조광상、억욱상여성선격소적관계。방법선취진단부합국제질병분류진단표준적쌍상정감장애조광발작환자30례화쌍상정감장애억욱발작환자30례，입조후급치료1개월후검측성선격소（6항）。결과쌍상조광조남성환자치료전혈청고동수평현저고우치료후급건강대조조고동수평，쌍상억욱조환자치료전혈청자이순（E2）수평현저저우치료후혈청 E2수평급건강대조조 E2수평。결론고동여쌍상조광남성환자상관，E2여쌍상억욱환자상관。
Objective To investigate the relationship of bipolar mania ,bipolar depression and sex hormone lev‐els .Methods To select 30 patients with bipolar mania (bipolar mania group) and 30 patients with bipolar depression (bipolar depression group) diagnosed according to the 10th revision of the International Classification of Diseases ,and to detect the sex hormone (6 items) levels respectively before and after one‐month treatment .Results Serum testos‐terone (T ) of male patients in bipolar mania group before treatment significantly higher than after treatment and that of normal control group .Serum estradiol (E2 ) levels of the patients in bipolar depression group before treatment was significantly lower than after treatment and that of normal control group .Conclusion Testosterone is associated with bipolar mania in male patients ,while estradiol is associated with bipolar depression .