化学通报（网络版）
化學通報（網絡版）
화학통보（망락판）
Chemistry Online
2015年
12期
1-9
,共9页
喻聪聪%徐余幸%管全银%赵国良
喻聰聰%徐餘倖%管全銀%趙國良
유총총%서여행%관전은%조국량
镉金属有机配合物%2-(4’-羧基苯基)咪唑-4,5-二羧酸%荧光光谱%DNA%BSA
鎘金屬有機配閤物%2-(4’-羧基苯基)咪唑-4,5-二羧痠%熒光光譜%DNA%BSA
력금속유궤배합물%2-(4’-최기분기)미서-4,5-이최산%형광광보%DNA%BSA
Cd MOF%2-(4’-Carboxyphenyl)-1H-imidazole-4,5-dicarboxylic acid%Photoluminescence%DNA%BSA
用缩合氧化反应，成功合成了一个新的咪唑羧酸配体2-(4’-羧基苯基)咪唑-4,5-二羧酸(H4CPhIDC)。在水热条件下以 H4CPhIDC 为主配体，邻菲咯啉(phen)为辅助配体，合成了镉的六核金属有机配合物[Cd6(CPhIDC)(HCPhIDC)2(H2CPhIDC)(phen)6]·H2O (MOF)。H4CPhIDC配体在该配合物中呈现出不同的去质子模式 H2CPhIDC2-、HCPhIDC3-、CPhIDC4-，从而形成了一个新的六核(3,3,4,5)-连接拓扑结构。测定了配体和配合物的固体荧光光谱，并用溴化乙锭荧光探针测定了配体和配合物与DNA及BSA的作用，结果表明，配合物对生物大分子的作用更强些。CCDC：969815。
用縮閤氧化反應，成功閤成瞭一箇新的咪唑羧痠配體2-(4’-羧基苯基)咪唑-4,5-二羧痠(H4CPhIDC)。在水熱條件下以 H4CPhIDC 為主配體，鄰菲咯啉(phen)為輔助配體，閤成瞭鎘的六覈金屬有機配閤物[Cd6(CPhIDC)(HCPhIDC)2(H2CPhIDC)(phen)6]·H2O (MOF)。H4CPhIDC配體在該配閤物中呈現齣不同的去質子模式 H2CPhIDC2-、HCPhIDC3-、CPhIDC4-，從而形成瞭一箇新的六覈(3,3,4,5)-連接拓撲結構。測定瞭配體和配閤物的固體熒光光譜，併用溴化乙錠熒光探針測定瞭配體和配閤物與DNA及BSA的作用，結果錶明，配閤物對生物大分子的作用更彊些。CCDC：969815。
용축합양화반응，성공합성료일개신적미서최산배체2-(4’-최기분기)미서-4,5-이최산(H4CPhIDC)。재수열조건하이 H4CPhIDC 위주배체，린비각람(phen)위보조배체，합성료력적륙핵금속유궤배합물[Cd6(CPhIDC)(HCPhIDC)2(H2CPhIDC)(phen)6]·H2O (MOF)。H4CPhIDC배체재해배합물중정현출불동적거질자모식 H2CPhIDC2-、HCPhIDC3-、CPhIDC4-，종이형성료일개신적륙핵(3,3,4,5)-련접탁복결구。측정료배체화배합물적고체형광광보，병용추화을정형광탐침측정료배체화배합물여DNA급BSA적작용，결과표명，배합물대생물대분자적작용경강사。CCDC：969815。
A novel imidazole carboxylic acid ligand, 2-(4’-carboxyphenyl)-1H-imidazole-4,5-dicarboxylic acid (H4CPhIDC) was prepared by condensation and oxidation reactions, and its metal-organic framework (MOF) [Cd6(CPhIDC)(HCPhIDC)2(H2CPhIDC)(phen)6]·H2O (phen=1,10-phenanthroline) was synthesized by solvothermal reaction. The H4CPhIDC ligand presents different deprotonated motifs of H2CPhIDC2-, HCPhIDC3-, and CPhIDC4- in this MOF and thus to form a new six-core (3,3,4,5)-connected topology. Meanwhile, the fluorescence properties of the ligand and the MOF in the solid state were determined. DNA and BSA binding properties of the ligand and the MOF were investigated. The results showed that the complex has much stronger interaction with biological macromolecules than the ligand. CCDC: 969815.
