CAJ | 학술논문

研究了作为渔业副产品且药食同源的海蛾（Pegasus laternarius Cuvier）的抗氧化功效和活性物质。以自由基清除活性为导向，筛选了海蛾的最佳提取方法，对并最佳提取物的不同极性萃取部位进行抗氧化筛选，随后用色谱、波谱技术对活性部位进行化学成分的分离和鉴定。研究确定75％乙醇为最佳提取溶剂，提取总膏萃取后的乙酸乙酯和正丁醇部位为抗氧化活性部位；在活性部位分离纯化5个化合物，分别鉴定为胆甾醇、（2S，3S，4R，8E）-8，9-二脱氢植物鞘氨醇（2’R）-2’-羟基脂肪酰胺、胆甾醇硫酸酯、对羟基苯甲醛和牛磺酸。研究结果表明，海蛾提取物抗氧化作用明确，活性部位为乙酸乙酯和正丁醇萃取部位，活性部位的化学成分研究为其进一步药效研究奠定了物质基础。
연구료작위어업부산품차약식동원적해아（Pegasus laternarius Cuvier）적항양화공효화활성물질。이자유기청제활성위도향，사선료해아적최가제취방법，대병최가제취물적불동겁성췌취부위진행항양화사선，수후용색보、파보기술대활성부위진행화학성분적분리화감정。연구학정75％을순위최가제취용제，제취총고췌취후적을산을지화정정순부위위항양화활성부위；재활성부위분리순화5개화합물，분별감정위담치순、（2S，3S，4R，8E）-8，9-이탈경식물초안순（2’R）-2’-간기지방선알、담치순류산지、대간기분갑철화우광산。연구결과표명，해아제취물항양화작용명학，활성부위위을산을지화정정순췌취부위，활성부위적화학성분연구위기진일보약효연구전정료물질기출。
The paper studied the antioxidant functions and active constitutes of Seamoth Pegasus laternarius Cuvier,known as a by-product of fishery and having the homology of medicine and food.The extraction method was optimized and guided by radicals scavenging tests.Different fractions of the extract were screened for their antioxidant functions, and the active fractions were studied for their chemical constitutes by chromatograph.75% alcohol was determined to be the best extract solvent,and ethyl acetate and n-Butnol fractions were considered to be the active fractions.Five compounds were identified as cholesterol,(2S,3S, 4R,8E )-8,9-didehydro-phytosphingosine (2 ’R )-2 ’-hydroxy fatty amides, cholesterol sulphate, p-hydrobenzaldehyde,and taurine.The antioxidant function of the Seamoth extract is clear,and the active fractions are ethyl acetate and n-Butnol fractions.The chemical study could provide material basis for the continuous drug efficacy research of Seamoth.