CAJ | 학술논문

以同时提供钆源和碳源的钆喷酸单葡甲胺为前驱体,利用微波作为加热手段实现分子水平上的搅拌,达到低温、短时间内制得均匀的小粒度Gd3+掺杂碳量子点（ Gd3+/CQDs-MH）的目的。当前驱体在250℃下微波水热反应45 min时,获得的Gd3+/CQDs-MH表现出较高的量子产率和极强的磁共振性能,避免了传统加热方式对碳量子点的发光能力和弛豫性能极难同时提高的矛盾。该条件下合成出尺寸约1.0 nm的碳量子点,其荧光量子产率为11.0%,Gd3+的掺杂质量分数达16.9%,纵向弛豫性能高达4545.3 mmol-1·L·s-1（[Gd3+]=0.01 mmol·L-1）。并且,该碳量子点对HeLa细胞无明显毒性,有望用作高弛豫性能和高发光性能的磁共振-荧光双模态探针。
이동시제공구원화탄원적구분산단포갑알위전구체,이용미파작위가열수단실현분자수평상적교반,체도저온、단시간내제득균균적소립도Gd3+참잡탄양자점（ Gd3+/CQDs-MH）적목적。당전구체재250℃하미파수열반응45 min시,획득적Gd3+/CQDs-MH표현출교고적양자산솔화겁강적자공진성능,피면료전통가열방식대탄양자점적발광능력화이예성능겁난동시제고적모순。해조건하합성출척촌약1.0 nm적탄양자점,기형광양자산솔위11.0%,Gd3+적참잡질량분수체16.9%,종향이예성능고체4545.3 mmol-1·L·s-1（[Gd3+]=0.01 mmol·L-1）。병차,해탄양자점대HeLa세포무명현독성,유망용작고이예성능화고발광성능적자공진-형광쌍모태탐침。
Using gadopentetic acid monomeglumine ( GdPM) as precursor to provide simultaneously the carbon source and gadolinium (3 +) source, gadolinium-doped carbon quantum dots ( Gd3+/CQDs-MH) with uniformly small size were obtained at a mild condition by microwave hydrothermal method which can realize a molecular level mixing. When GdPM was pyrolyzed under 250 ℃ for 45 min, Gd3+/CQDs-MH with high quantum yield ( QY) and longitudinal relaxation rate ( r1 ) were ob-tained. The contradiction between quantum yield and the relaxation properties has been well bal-anced, which is very difficult to avoid using traditional heating method. The prepared Gd3+/CQDs-MH with an average diameter of about 1 . 0 nm show little cell toxicity and exhibit a high photolumi-nescence quantum yield of 11. 0%, as well as a high r1 value of 4 545. 3 mmol-1 · L · s-1 ([Gd3+] =0. 01 mmol·L-1) with the doping mass fraction of gadolinium (3 +) of 16. 9%. Therefore, the Gd3+/CQDs-MH show big possibility for application in magnetic resonance/fluores-cence bimodal molecular imaging.