CAJ | 학술논문

功能性消化不良（ FD）是一种常见的功能性胃肠病，其发病机制尚未完全明确。近来研究发现FD患者胃肠道黏膜存在低度炎症，其中黏膜屏障功能受损、精神心理因素、脑-肠轴活动异常可能促进炎症形成，并且可能与FD的发生、发展相关。本文就胃肠道黏膜低度炎症在FD中的研究进展作一综述。
공능성소화불량（ FD）시일충상견적공능성위장병，기발병궤제상미완전명학。근래연구발현FD환자위장도점막존재저도염증，기중점막병장공능수손、정신심리인소、뇌-장축활동이상가능촉진염증형성，병차가능여FD적발생、발전상관。본문취위장도점막저도염증재FD중적연구진전작일종술。
Functional dyspepsia( FD)is a common functional gastrointestinal disorder,its pathogenesis has not been fully clarified. Recent studies showed that gastrointestinal mucosal low-grade inflammation had been found in patients with FD,and impaired mucosal integrity,psychological factor and abnormal brain-gut axis may promote the inflammation formation,which may also contribute to the onset and persistence of FD. This article reviewed the advances in study on gastrointestinal mucosal low-grade inflammation in FD.