CAJ | 학술논문

目的探讨改良法无肝素透析的临床应用效果. 方法选取2011年3月至2015年2月我院收治有出血倾向长期透析患者34例随机分为改良组和常规组各17例, 分别采用改良法无肝素透析和传统无肝素透析, 连续透析2月后, 比较两组的凝血功能、肾功能及透析器凝血发生率. 结果两组患者PT、 TT、 APTT、 Fb及BUN水平比较差异无统计学意义 (P>0.05). 改良组患者Cr水平为 ( 452.3 士 32.6) μmol/L, 显著低于常规组的 ( 489.3 士 33.2) μmo1/L ( P <0.05). 改良组患者凝血发生率为5.88%, 显著低于常规组的35.29% (P<0.05). 结论改良法无肝素透析可提高透析效果, 降低透析器凝血发生率, 且不影响患者凝血功能, 具有较高的安全性.
목적 탐토개량법무간소투석적림상응용효과. 방법 선취2011년3월지2015년2월아원수치유출혈경향장기투석환자34례수궤분위개량조화상규조각17례, 분별채용개량법무간소투석화전통무간소투석, 련속투석2월후, 비교량조적응혈공능、 신공능급투석기응혈발생솔. 결과 량조환자PT、 TT、 APTT、 Fb급BUN수평비교차이무통계학의의 (P>0.05). 개량조환자Cr수평위 ( 452.3 사 32.6) μmol/L, 현저저우상규조적 ( 489.3 사 33.2) μmo1/L ( P <0.05). 개량조환자응혈발생솔위5.88%, 현저저우상규조적35.29% (P<0.05). 결론 개량법무간소투석가제고투석효과, 강저투석기응혈발생솔, 차불영향환자응혈공능, 구유교고적안전성.
Objective To explore the clinical effect of modified heparin-free hemodialysis. Methods 34 cases of long-term dialysis patients with bleeding tendency admitted to our hospital from March 2011 to February 2015 were randomly divided into modified group (n=17, modified heparin-free hemodialysis) and routine group (n=17, traditional heparin-free hemodialysis). After two months of continuous dialysis, the coagulation function, renal function and the incidence of dialyzer clotting were compared. Results No statistical difference was found between two groups in the levels of PT, TT, APTT, Fb and BUN (P>0.05). The Cr level of modified group was (452.3 ± 32.6)μmol/L, significantly lower than (489.3 ± 33.2) μmol/L of routine group (P <0.05). The incidence of coagulation of modified group was 5.88%, significantly lower than 35.29% of routine group (P <0.05). Conclusions Modified heparin-free hemodialysis can improve the dialysis effect, reduce the incidence of dialyzer clotting, which does not affect the function of blood coagulation and has high security.