临床医学工程
臨床醫學工程
림상의학공정
Clinical Medical & Engineering
2015年
11期
1448-1450
,共3页
高渗盐水%肾上腺素%毛细支气管炎%炎性细胞
高滲鹽水%腎上腺素%毛細支氣管炎%炎性細胞
고삼염수%신상선소%모세지기관염%염성세포
Hypertonic saline%Adrenaline%Capillary bronchitis%Inflammatory cell
目的 探讨高渗盐水配合肾上腺素吸入对毛细支气管炎的临床疗效. 方法 选择2013年1月至2014年12月在我院儿科就诊的毛细支气管炎患儿200例为研究对象, 随机分为观察组和对照组, 每组100例, 观察组将肾上腺素溶于高渗盐水行雾化吸入治疗, 对照组将万托林溶于生理盐水行雾化吸入治疗, 观察并比较两组患儿的临床症状改善所需时间及炎性细胞数量的变化情况. 结果 观察组喘憋、 咳嗽、 肺部喘鸣音及湿啰音的消失时间均明显少于对照组, 差异有统计学意义 (P<0.05). 观察组雾化吸入后5 d患儿的各项肺功能指标均明显优于对照组, 差异有统计学意义 (P<0.05). 两组雾化前后气道分泌物的炎性细胞总数、 中性粒细胞数及淋巴细胞数差值比较, 观察组均明显高于对照组, 差异有统计学意义 (P<0.05). 结论 应用肾上腺素溶于高渗盐水行雾化吸入治疗小儿毛细支气管炎, 可缩短患儿的临床症状改善时间, 有效减少气道炎性细胞的聚积, 减轻气道的炎性反应, 疗效可靠.
目的 探討高滲鹽水配閤腎上腺素吸入對毛細支氣管炎的臨床療效. 方法 選擇2013年1月至2014年12月在我院兒科就診的毛細支氣管炎患兒200例為研究對象, 隨機分為觀察組和對照組, 每組100例, 觀察組將腎上腺素溶于高滲鹽水行霧化吸入治療, 對照組將萬託林溶于生理鹽水行霧化吸入治療, 觀察併比較兩組患兒的臨床癥狀改善所需時間及炎性細胞數量的變化情況. 結果 觀察組喘憋、 咳嗽、 肺部喘鳴音及濕啰音的消失時間均明顯少于對照組, 差異有統計學意義 (P<0.05). 觀察組霧化吸入後5 d患兒的各項肺功能指標均明顯優于對照組, 差異有統計學意義 (P<0.05). 兩組霧化前後氣道分泌物的炎性細胞總數、 中性粒細胞數及淋巴細胞數差值比較, 觀察組均明顯高于對照組, 差異有統計學意義 (P<0.05). 結論 應用腎上腺素溶于高滲鹽水行霧化吸入治療小兒毛細支氣管炎, 可縮短患兒的臨床癥狀改善時間, 有效減少氣道炎性細胞的聚積, 減輕氣道的炎性反應, 療效可靠.
목적 탐토고삼염수배합신상선소흡입대모세지기관염적림상료효. 방법 선택2013년1월지2014년12월재아원인과취진적모세지기관염환인200례위연구대상, 수궤분위관찰조화대조조, 매조100례, 관찰조장신상선소용우고삼염수행무화흡입치료, 대조조장만탁림용우생리염수행무화흡입치료, 관찰병비교량조환인적림상증상개선소수시간급염성세포수량적변화정황. 결과 관찰조천별、 해수、 폐부천명음급습라음적소실시간균명현소우대조조, 차이유통계학의의 (P<0.05). 관찰조무화흡입후5 d환인적각항폐공능지표균명현우우대조조, 차이유통계학의의 (P<0.05). 량조무화전후기도분비물적염성세포총수、 중성립세포수급림파세포수차치비교, 관찰조균명현고우대조조, 차이유통계학의의 (P<0.05). 결론 응용신상선소용우고삼염수행무화흡입치료소인모세지기관염, 가축단환인적림상증상개선시간, 유효감소기도염성세포적취적, 감경기도적염성반응, 료효가고.
Objective To explore the clinical efficacy of hypertonic saline combined with adrenaline inhalation for the treatment of capillary bronchitis. Methods 200 cases of children with capillary bronchitis admitted to pediatrics department of our hospital from January 2013 to December 2014 were selected and randomly divided into two groups, with 100 cases in each group. Children in the observation group were given epinephrine dissolved in hypertonic saline for inhalation, while children in the control group were given ventolin dissolved in normal saline for inhalation. The time for improvement of clinical symptoms, and changes of number of inflammatory cells were observed and compared. Results The disappearance time of asthma suppress, cough, lung wheeze and moist rales of the observation group were significantly shorter than those of the control group (P<0.05). 5 days after inhalation, the lung function parameters of the observation group were significantly better than those of the control group (P<0.05). The differential values of total number of inflammatory cells, the number of neutrophils and number of lymphocytes before and 5 days after inhalation of the observation group were significantly higher than those of the control group (P<0.05). Conclusions Aerosol inhalation with epinephrine dissolved in hypertonic saline has reliable effect for children with capillary bronchitis, which can shorten the time for improvements of clinical symptoms, reduce the accumulation of inflammatory cells in the airways, and lighten the inflammatory of airway.
