CAJ | 학술논문

目的：运用SysmexXE－2100D血液分析仪，探索筛选异型淋巴细胞的可行性。方法分析4DIFF散点图a区域异常和正常各60例血常规标本，并分为A、B 2组，同时进行血涂片染色，手工显微镜检查异型淋巴细胞，以显微镜检查的结果作为金标准判断4DIFF散点图a区域异常提示的准确性。结果 A组中检出异型淋巴细胞55例，5例未检出；B组中检出异型淋巴细胞3例，57例未检出。敏感度94．83％，特异度91．94％，阳性预测值91．66％，阴性预测值95％，准确度93．33％。四格表χ2检验，A组：χ2＝5．217，P＝0．022，差异有统计学意义（P＜0．05）；B组：χ2＝3．077，P＝0．079，差异无统计学意义（P＞0．05）。结论根据sysmexXE－2100D血液分析仪4DIFF散点图a区域异常提示筛选异型淋巴细胞，切实可行，效果满意。
목적：운용SysmexXE－2100D혈액분석의，탐색사선이형림파세포적가행성。방법분석4DIFF산점도a구역이상화정상각60례혈상규표본，병분위A、B 2조，동시진행혈도편염색，수공현미경검사이형림파세포，이현미경검사적결과작위금표준판단4DIFF산점도a구역이상제시적준학성。결과 A조중검출이형림파세포55례，5례미검출；B조중검출이형림파세포3례，57례미검출。민감도94．83％，특이도91．94％，양성예측치91．66％，음성예측치95％，준학도93．33％。사격표χ2검험，A조：χ2＝5．217，P＝0．022，차이유통계학의의（P＜0．05）；B조：χ2＝3．077，P＝0．079，차이무통계학의의（P＞0．05）。결론근거sysmexXE－2100D혈액분석의4DIFF산점도a구역이상제시사선이형림파세포，절실가행，효과만의。
Objective To explore the feasibility of atypical lymphocyte screening by the SysmexXE-2100D hema-tology analyzer.Methods Blood specimens showing abnormal and normala-area in 4DIFF scattergrams were obtained and labeled as Group A and Group B ( n=60) .Meanwhile, blood smear staining was conducted, and atypical lympho-cytes were examined through manual microscopic examination.The results of microscopic examination was adopted as a gold standard and compared with the data from 4DIFF scattergrams.Results There were 55 specimens with atypical lymphocytes in Group A, while 5 specimens were not detected.In contrast, there were 3 specimens with atypical lympho-cytes, while 57 specimens were not detected.The sensitivity was 94.83%.The specificity was 91.94%.The positive and negative predictive values were 91.66%and 95%, respectively.The accuracy was 93.33%.According to the four-fold tableχ2 test, Group A showed χ2 =5.217, P=0.022, with statistically significant difference (P<0.05), while Group B showedχ2 =3.077, P=0.079, without statistically significant difference (P>0.05).Conclusion It is feasi-ble to indicate the presence of atypical lymphocytes using abnormality ina-area of 4DIFF scattergram by the sysmexXE-2100D hematology analyzer.