CAJ | 학술논문

目的：探讨PCT检测在细菌性感染中的临床应用。方法采用回顾性分析法，随机选取该院2014年3月-2015年6月期间收治的68例细菌感染患者的临床资料为研究对象，根据患者有无脓毒症将患者分为两组，脓毒症组和非脓毒症组，其中脓毒症组患者44例，非脓毒症组患者24例。利用万孚飞测免疫荧光仪测定患者血清PCT阳性率，比较在革兰氏阳性菌和革兰氏阴性菌中PCT阳性率的差异。结果以PCT≥0.5 ng/mL为阳性阈值，PCT阳性率为88.24豫；不同致病菌所致感染组间PCT阳性率差异无统计学意义(P>0.05)；以PCT≥2.0 ng/mL为脓毒症的阳性阈值，发现脓毒症组患者PCT含量明显高于非脓毒症组患者，差异有统计学意义(P<0.05)；PCT对脓毒症的临床诊断特异性和灵敏度分别为：100豫、81.81豫。结论血清PCT是鉴别细菌感染引发脓毒症的较为准确的检测手段。
목적：탐토PCT검측재세균성감염중적림상응용。방법채용회고성분석법，수궤선취해원2014년3월-2015년6월기간수치적68례세균감염환자적림상자료위연구대상，근거환자유무농독증장환자분위량조，농독증조화비농독증조，기중농독증조환자44례，비농독증조환자24례。이용만부비측면역형광의측정환자혈청PCT양성솔，비교재혁란씨양성균화혁란씨음성균중PCT양성솔적차이。결과이PCT≥0.5 ng/mL위양성역치，PCT양성솔위88.24예；불동치병균소치감염조간PCT양성솔차이무통계학의의(P>0.05)；이PCT≥2.0 ng/mL위농독증적양성역치，발현농독증조환자PCT함량명현고우비농독증조환자，차이유통계학의의(P<0.05)；PCT대농독증적림상진단특이성화령민도분별위：100예、81.81예。결론혈청PCT시감별세균감염인발농독증적교위준학적검측수단。
Objective To investigate the clinical application of detection of PCT in bacterial infection. Methods A retro-spective analysis, select our hospital during March 2014 - June 2015, the clinical data of 68 patients with bacterial infec-tions were treated as the research object, according to the presence of sepsis patients divided the patients into two groups, sepsis and sepsis group, including 44 patients with sepsis group, 24 cases of sepsis patients. Wan Fu fly immunofluores-cence measurement instrument has been applied to the determination of serum PCT in patients with positive rate, comparing the gram-positive bacteria and gram-negative bacteria of PCT in the difference of positive rate. Results PCT acuity 0.5 ng/mL for positive threshold, PCT positive rate is 88.24%;Different pathogenic bacteria caused by the infection rate of positive of PCT no obvious differences between groups, P>0.05, there was no statistical significance; PCT acuity 2.0 ng/mL for sepsis positive threshold, found that the content of PCT in patients with sepsis group was obviously higher than that of the sepsis patients, by statistical comparison,P<0.05, there was statistically significant; PCT the clinical diagnostic sensitivity and specificity of sepsis is respectively:100%, 81.81%.Conclusion The serum PCT was to identify bacterial infection caused by sepsis is relatively accurate means of detection.