CAJ | 학술논문

目的：观察地佐辛在局麻鼻内镜手术中的镇痛效果及安全性。方法180例局麻鼻内镜手术患者随机分成地佐辛组及非地佐辛组，各90例，地佐辛组术前使用地佐辛及基础用药(阿托品及蛇毒血凝酶)，非地佐辛组术前只使用基础用药(阿托品及蛇毒血凝酶)，术中观察并记录患者不良反应情况，术毕行视觉模拟评分( VAS)。结果两组患者疼痛程度VAS比较，地佐辛组主要为轻度疼痛(74/90)，非地佐辛组主要为中度疼痛(63/90)，差异有统计学意义(P<0.05)；不良反应比较，地佐辛组不良反应共13例，非地佐辛组共18例，差异无统计学意义(P>0.05)。结论地佐辛用于鼻内镜手术中镇痛，效果明显，无明显不良反应，值得临床广泛推广。
목적：관찰지좌신재국마비내경수술중적진통효과급안전성。방법180례국마비내경수술환자수궤분성지좌신조급비지좌신조，각90례，지좌신조술전사용지좌신급기출용약(아탁품급사독혈응매)，비지좌신조술전지사용기출용약(아탁품급사독혈응매)，술중관찰병기록환자불량반응정황，술필행시각모의평분( VAS)。결과량조환자동통정도VAS비교，지좌신조주요위경도동통(74/90)，비지좌신조주요위중도동통(63/90)，차이유통계학의의(P<0.05)；불량반응비교，지좌신조불량반응공13례，비지좌신조공18례，차이무통계학의의(P>0.05)。결론지좌신용우비내경수술중진통，효과명현，무명현불량반응，치득림상엄범추엄。
Objective To observe the analgesic effect and safety of dezocine in endoscopic nasal surgery under local anesthesia. Methods 180 patients received endoscopic nasal surgery were randomly divided into dezocine group and non-dezocine group,the dezocine group were given dezocine and basis pharmacy(Atropine and Hemocoagulase),and the other group were given only basis pharmacy(Atropine and Hemocoagulase). Adverse effects in all patients were observed and recorded. Visual analog scale ( VAS ) was used for rating the level of pain after operation. Results The dezocine group was mainly with mild pain (74/90),the other group was mainly with moderate pain (63/90). The VAS scores of both group were significant (P<0. 05). There were no significant(P>0. 05) differences in the incidence of adverse effects,the dezocine group had a total of 13 cases with adverse reactions,and the other group had a total of 18 cases. Conclusions Dezocine can provide good analgesic effect in endoscopic sinus surgery,with little obvious adverse effects,which is worth clinical promotion.