CAJ | 학술논문

目的：探讨Hp相关性胃溃疡的治疗与进展。方法对该科2013年3月-2015年3月收治的264例Hp相关性胃溃疡患者采取分组治疗，A组89例采用甲硝唑、头孢羟氨苄、雷尼替丁三联治疗，B组89例采用甲硝唑、头孢羟氨苄、奥美拉唑三联治疗，C组加入枸橼酸铋钾治疗，观察3组疗效。结果3组在溃疡愈合方面比较差异无统计学意义(P>0.05)；B、C组在Hp消除和复发方面显著优于A组(P<0.05)，C组Hp清除率优于B组(P<0.05)，B、C两组复发率比较差异无统计学意义(P>0.05)。结论治疗时根据患者情况选择合适的治疗方案，可提高疗效，减少复发，促进康复。
목적：탐토Hp상관성위궤양적치료여진전。방법대해과2013년3월-2015년3월수치적264례Hp상관성위궤양환자채취분조치료，A조89례채용갑초서、두포간안변、뢰니체정삼련치료，B조89례채용갑초서、두포간안변、오미랍서삼련치료，C조가입구연산필갑치료，관찰3조료효。결과3조재궤양유합방면비교차이무통계학의의(P>0.05)；B、C조재Hp소제화복발방면현저우우A조(P<0.05)，C조Hp청제솔우우B조(P<0.05)，B、C량조복발솔비교차이무통계학의의(P>0.05)。결론치료시근거환자정황선택합괄적치료방안，가제고료효，감소복발，촉진강복。
Objective To investigate the advances in the treatment of Hp related gastric ulcer. Methods 264 cases with Hp related gastric ulcer admitted in our department from March 2013 to March 2015 were divided into group A (89 cases) and group B (89 cases) and group C. Patients in group A were treated by metronidazole, cefadroxil and ranitidine triple therapy, those in group B were treated by metronidazole, cefadroxil and omeprazole triple therapy, and those in group C were treated by adding colloidal bismuth subcitrate. And the treatment effect of the 3 groups was observed. Results There was no differ-ence in terms of gastric ulcer healing between the 3 groups (P>0.05). Group B and group C were much better than group A in the removal rate of Hp and recurrence rate(P<0.05). Group C had higher removal rate of Hp than group B(P<0.05). There was no statistically significant difference in the recurrence rate between group B and group C(P>0.05). Conclusion In order to improve the efficacy and promote the rehabilitation, the treatment regimen should be selected in accordance with the conditions of the patients.