CAJ | 학술논문

目的：分析怀化地区2型糖尿病(T2DM)住院患者糖尿病慢性并发症临床特点。方法收集本科室住院1033例2型糖尿病患者临床资料,登记其生活背景,以及实验室检查指标(血糖、血脂、胰岛素、24 h尿白蛋白)。根据国际临床分类法,眼底荧光造影,24 h尿白蛋白情况,神经肌电图,彩超检查,头部CT,心电图以及酶学诊断糖尿病视网膜病变、糖尿病肾脏病变、糖尿病周围神经病变、糖尿病大血管并发症,并进行对比分析。结果就诊2型糖尿病患者女性年龄、糖尿病病程、高血压病史状况高于男性(P<0.05),女性高血脂、吸烟、喝酒患者较男性少(P=0.005,0.000,0.000)。女性糖尿病视网膜病变及糖尿病周围神经病变患病率明显高于男性(P=0.000,0.000)；糖尿病肾病的患病率则以男性多见(P=0.038)。大血管病变患病率没有性别差异。结论怀化地区糖尿病慢性并发症与年龄、糖尿病病程、肥胖、吸烟、血糖控制、高血压、高血脂有密切的关系；糖尿病慢性并发症存在明显的性别差异。
목적：분석부화지구2형당뇨병(T2DM)주원환자당뇨병만성병발증림상특점。방법수집본과실주원1033례2형당뇨병환자림상자료,등기기생활배경,이급실험실검사지표(혈당、혈지、이도소、24 h뇨백단백)。근거국제림상분류법,안저형광조영,24 h뇨백단백정황,신경기전도,채초검사,두부CT,심전도이급매학진단당뇨병시망막병변、당뇨병신장병변、당뇨병주위신경병변、당뇨병대혈관병발증,병진행대비분석。결과취진2형당뇨병환자녀성년령、당뇨병병정、고혈압병사상황고우남성(P<0.05),녀성고혈지、흡연、갈주환자교남성소(P=0.005,0.000,0.000)。녀성당뇨병시망막병변급당뇨병주위신경병변환병솔명현고우남성(P=0.000,0.000)；당뇨병신병적환병솔칙이남성다견(P=0.038)。대혈관병변환병솔몰유성별차이。결론부화지구당뇨병만성병발증여년령、당뇨병병정、비반、흡연、혈당공제、고혈압、고혈지유밀절적관계；당뇨병만성병발증존재명현적성별차이。
Objective To investigate the clinical characteristics in patients with chronic complication of type 2 diabe-tes in Huaihua. Methods 1033 patients with T2DM were elected from the departmant of enducriology,the First People’s Hospital of Huaihua from January 2012 to January 2013. Their living background was registered,as well as indexes about labo-ratory examination (blood glucose,blood lipid,blood insulin and 24 h urinary albumin). Diabetic retinopathy,diabetic renal disease,diabetic peripheral neuropathy ( DPN) and macrovascular complications in diabetes were diagnosed according to inter-national clinical classification and 24 h urinary albumin,neural electromyologram ( EMG) ,CT of head,electrocardiogram and enzymological method. Result (1) Female patients compared with male patients in 1 033 patients diagnosed as T2DM, showed increase in age,the duration of diabetes,and hypertention ( P<0. 05 );But showed decrease in hyperlipidemia,smok-ing and drinking ( P=0. 005,0. 000,0. 000 );(2) The female diabetic retinopathy and diabetic peripheral neuropathy preva-lence were significantly higher than male (P=0. 000,0. 000 ),but the prevalence of diabetic nephropathy was lower than male (P=0. 038);(3) Macroangiopathy had no significant gender difference. Conclusion Age,duration of diabetes,obe-sity,smoking,blood glucose control,hypertension,hyperlipidemia are closely related to the T2DM diabetic microangiopathy. And this study showed the chronic complication of type 2 diabetes had different patterns in males and females.