中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
Chinese Journal of Biochemical Pharmaceutics
2015年
10期
51-53
,共3页
参芪扶正注射液%腹腔镜结肠癌根治术%CA19-9%CRP%CD4+淋巴细胞亚群
參芪扶正註射液%腹腔鏡結腸癌根治術%CA19-9%CRP%CD4+淋巴細胞亞群
삼기부정주사액%복강경결장암근치술%CA19-9%CRP%CD4+림파세포아군
ShenQi FuZheng injection%laparoscopic radical resection of colon cancer%carbohydrate antigen 19-9%C-reaction protein%CD4 +lymphocyte subsets
目的 探讨参芪扶正注射液对腹腔镜结肠癌根治术患者术后血清糖链抗原19-9(carbohydrate antigen 19-9,CA19-9)、C反应蛋白(C-reaction protein,CRP)、CD4 +淋巴细胞亚群的影响.方法 收集收治的进行腹腔镜结肠癌根治术的患者58例,根据用药不同分为对照组和实验组,每组各29例,术后分别给予相应的药物治疗,治疗结束后,对所有患者的血清CA19-9、CRP及静脉血T淋巴细胞水平进行检测.结果 与治疗前比较,2组患者血清CA19-9、CRP水平降低(P<0.05) ,静脉血CD4 +细胞、CD4+/CD8 +以及NK细胞水平升高(P<0.05).治疗后与对照组比较,实验组患者血清CA19-9、CRP水平较低(P<0.05);实验组患者的静脉血CD4 +细胞、CD4 +/CD8 +以及NK细胞水平较高(P<0.05).结论 参芪扶正注射液能够显著降低腹腔镜结肠癌根治术患者术后血清CA19-9、CRP水平,提高静脉血CD4+细胞、CD4 +/CD8 +以及NK细胞水平,改善免疫功能,对临床有指导意义.
目的 探討參芪扶正註射液對腹腔鏡結腸癌根治術患者術後血清糖鏈抗原19-9(carbohydrate antigen 19-9,CA19-9)、C反應蛋白(C-reaction protein,CRP)、CD4 +淋巴細胞亞群的影響.方法 收集收治的進行腹腔鏡結腸癌根治術的患者58例,根據用藥不同分為對照組和實驗組,每組各29例,術後分彆給予相應的藥物治療,治療結束後,對所有患者的血清CA19-9、CRP及靜脈血T淋巴細胞水平進行檢測.結果 與治療前比較,2組患者血清CA19-9、CRP水平降低(P<0.05) ,靜脈血CD4 +細胞、CD4+/CD8 +以及NK細胞水平升高(P<0.05).治療後與對照組比較,實驗組患者血清CA19-9、CRP水平較低(P<0.05);實驗組患者的靜脈血CD4 +細胞、CD4 +/CD8 +以及NK細胞水平較高(P<0.05).結論 參芪扶正註射液能夠顯著降低腹腔鏡結腸癌根治術患者術後血清CA19-9、CRP水平,提高靜脈血CD4+細胞、CD4 +/CD8 +以及NK細胞水平,改善免疫功能,對臨床有指導意義.
목적 탐토삼기부정주사액대복강경결장암근치술환자술후혈청당련항원19-9(carbohydrate antigen 19-9,CA19-9)、C반응단백(C-reaction protein,CRP)、CD4 +림파세포아군적영향.방법 수집수치적진행복강경결장암근치술적환자58례,근거용약불동분위대조조화실험조,매조각29례,술후분별급여상응적약물치료,치료결속후,대소유환자적혈청CA19-9、CRP급정맥혈T림파세포수평진행검측.결과 여치료전비교,2조환자혈청CA19-9、CRP수평강저(P<0.05) ,정맥혈CD4 +세포、CD4+/CD8 +이급NK세포수평승고(P<0.05).치료후여대조조비교,실험조환자혈청CA19-9、CRP수평교저(P<0.05);실험조환자적정맥혈CD4 +세포、CD4 +/CD8 +이급NK세포수평교고(P<0.05).결론 삼기부정주사액능구현저강저복강경결장암근치술환자술후혈청CA19-9、CRP수평,제고정맥혈CD4+세포、CD4 +/CD8 +이급NK세포수평,개선면역공능,대림상유지도의의.
Objective To analyse effect of ShenQi FuZheng injection on serum carbohydrate antigen 19-9(CA19-9), C-reaction protein(CRP) and CD4 +lymphocyte subsets in patients after laparoscopic radical resection of colon cancer.Methods 58 patients after laparoscopic radical resection of colon cancer were collected.All patients were randomly divided into experimental group and control group according to the different drugs, 29 cases in each group.Patients were given the corresponding drug treatment after operation, after the treatment, the serum levels of CA19-9, CRP and venous blood T lymphocyte level were detected in all patients.Results Compared with before treatment, CA19-9 and CRP level in serum were lower (P<0.05) , CD4 +cells, CD4 +/CD8 +, and NK cells were higher(P<0.05);Compared with control group after treatment, the serum CA19-9 and CRP level were lower in the experimental group (P<0.05); the levels of venousblood CD4 +cells, CD4 +/CD8 +and NK cells were higher in the experimental group (P<0.05).Conclusion ShenQi FuZheng injection can significantly reduce the serum CRP and CA19-9 levels in patients after laparoscopic radical resection of colon cancer, improve the levels of venous blood CD4 +cells, CD4 +/CD8 +and NK cells, improve immune function, and have a guiding significance for clinica.
