中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
Chinese Journal of Biochemical Pharmaceutics
2015年
10期
73-75
,共3页
血液净化%维持性血透%心肌肌钙蛋白T/I%β2微球蛋白%白介素-6
血液淨化%維持性血透%心肌肌鈣蛋白T/I%β2微毬蛋白%白介素-6
혈액정화%유지성혈투%심기기개단백T/I%β2미구단백%백개소-6
blood purification%hemodialysis%cardiac troponin T/I%β2-microglobulin%interleukin-6
目的 探讨不同血液净化方式对维持性血透患者心肌肌钙蛋白T(cardiac troponinc T,cTnT)、心肌肌钙蛋白I(cardiac troponin I,cTnI)、β2-微球蛋白(β2-microglobulin,β2-MG)及白介素-6(interleukin-6,IL-6)水平的影响.方法 收集湖州市中心医院收治的进行维持性血液透析治疗的尿毒症患者60例,随机分为常规血液透析组(HD组)、血液透析联合血液灌流组(HD+HP组)以及血液透析滤过组(HDF组) ,每组各20例,分别给予相应的透析治疗,治疗结束后,对所有患者的血清cTnT、cTnI、β2-MG及IL-6水平进行检测.结果 治疗后,HDF组和HD+HP组患者血清cTnT、cTnI、β2-MG及IL-6水平显著低于HD组(P<0.05).结论 不同血液净化方式对维持性血透患者血清cTnT、cTnI、β2-MG及IL-6的清除效果不同,血液透析滤过和血液透析联合血液灌流具有更好的清除作用,对临床有指导意义.
目的 探討不同血液淨化方式對維持性血透患者心肌肌鈣蛋白T(cardiac troponinc T,cTnT)、心肌肌鈣蛋白I(cardiac troponin I,cTnI)、β2-微毬蛋白(β2-microglobulin,β2-MG)及白介素-6(interleukin-6,IL-6)水平的影響.方法 收集湖州市中心醫院收治的進行維持性血液透析治療的尿毒癥患者60例,隨機分為常規血液透析組(HD組)、血液透析聯閤血液灌流組(HD+HP組)以及血液透析濾過組(HDF組) ,每組各20例,分彆給予相應的透析治療,治療結束後,對所有患者的血清cTnT、cTnI、β2-MG及IL-6水平進行檢測.結果 治療後,HDF組和HD+HP組患者血清cTnT、cTnI、β2-MG及IL-6水平顯著低于HD組(P<0.05).結論 不同血液淨化方式對維持性血透患者血清cTnT、cTnI、β2-MG及IL-6的清除效果不同,血液透析濾過和血液透析聯閤血液灌流具有更好的清除作用,對臨床有指導意義.
목적 탐토불동혈액정화방식대유지성혈투환자심기기개단백T(cardiac troponinc T,cTnT)、심기기개단백I(cardiac troponin I,cTnI)、β2-미구단백(β2-microglobulin,β2-MG)급백개소-6(interleukin-6,IL-6)수평적영향.방법 수집호주시중심의원수치적진행유지성혈액투석치료적뇨독증환자60례,수궤분위상규혈액투석조(HD조)、혈액투석연합혈액관류조(HD+HP조)이급혈액투석려과조(HDF조) ,매조각20례,분별급여상응적투석치료,치료결속후,대소유환자적혈청cTnT、cTnI、β2-MG급IL-6수평진행검측.결과 치료후,HDF조화HD+HP조환자혈청cTnT、cTnI、β2-MG급IL-6수평현저저우HD조(P<0.05).결론 불동혈액정화방식대유지성혈투환자혈청cTnT、cTnI、β2-MG급IL-6적청제효과불동,혈액투석려과화혈액투석연합혈액관류구유경호적청제작용,대림상유지도의의.
Objective To analyse the effect of different blood purification methods on serum cardiac troponinc T (cTnT), cardiac troponinⅠ(cTnI), β2-microglobulin (β2-MG) and interleukin-6 (IL-6) levels in patients with maintenance hemodialysis.Methods 60 uremic patients treated with maintenance hemodialysis were collected.All patients were randomly divided into conventional hemodialysis group (HD group) , hemodialysis and hemoperfusion group (HD+HP group) and hemodiafiltration group (HDF group) , 20 cases in each group.Corresponding dialysis treatment was given, then the serum levels of cTnT, cTnI,β2-MG and IL-6 were detected in all patients post-treatment.Results After treatment, the serum cTnT, cTnI,β2-MG and IL-6 levels in HD+HP group and HDF group were lower than those in HD group (P<0.05).Conclusions Different blood purification methods have different effects on serum cTnT, cTnI, β2-MG and IL-6 levels in patients with maintenance hemodialysis, HDF and HD +HP have better scavenging effect, which has the guiding significance to clinical application.
