CAJ | 학술논문

目的:探讨联合检测心肌肌钙蛋白I(cTnI)和心型脂肪酸结合蛋白(H-FABP)对手足口病患儿心肌损伤的诊断价值.方法:将HFMD患儿198例分为心肌损伤组(42例)和心肌正常组(156例),52例健康儿童作为正常对照,检测各组入院第6、12、18、24、30、36 h血清H-FABP、cTnI.结果:与心肌正常组和对照组比较,心肌损伤组cTnI入院第 12、18、24 h 明显升高(P<0.05),H-FABP 入院第 6、12、18 h 明显升高(P<0.05).结论:血清 H-FABP 诊断HFMD患儿早期心肌损伤优于cTnI.
목적:탐토연합검측심기기개단백I(cTnI)화심형지방산결합단백(H-FABP)대수족구병환인심기손상적진단개치.방법:장HFMD환인198례분위심기손상조(42례)화심기정상조(156례),52례건강인동작위정상대조,검측각조입원제6、12、18、24、30、36 h혈청H-FABP、cTnI.결과:여심기정상조화대조조비교,심기손상조cTnI입원제 12、18、24 h 명현승고(P<0.05),H-FABP 입원제 6、12、18 h 명현승고(P<0.05).결론:혈청 H-FABP 진단HFMD환인조기심기손상우우cTnI.
Objective:To investigate the diagnostic value of joint detection of serum cardiac troponin I and H-FABP in children with hand-foot-mouth disease combined myocardial injury.Methods:198 cases of children with HFMD were divided myocardial injury group(42 cases) and no-myocardial injury group(156 cases) and 52 cases of healthy children as the control group,the serum H-FABP and cardiac troponin I of the three groups in the 6,12,18,24,30,36 hour after admission were detected.Results:Compared with no-myocardial injury group and the control group,the cTnI levels of the myocardial injury group increased more in 12,18,24 hour after admission,the H-FABP levels increased more in 6,12,18 hour after admission(P<0.05).Conclusions:The serum H-FABP had better diagnosis of early myocardial injury in children with HFMD than cTnI.