中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
Chinese Journal of Biochemical Pharmaceutics
2015年
10期
88-89,92
,共3页
利伐沙班%血塞通注射液%脊柱术后%深静脉血栓
利伐沙班%血塞通註射液%脊柱術後%深靜脈血栓
리벌사반%혈새통주사액%척주술후%심정맥혈전
rivaroxaban%Xuesaitong injection%after spinal surgery%deep venous thrombosis
目的 探讨利伐沙班与血塞通注射液联合应用对脊柱术后下肢深静脉血栓(deep venous thrombosis,DVT)的作用.方法 选取2013年5月~2015年5月承德市中心医院脊柱外科接受脊柱手术治疗的患者共90例,随机分为实验组和对照组,其中实验组45例,术后第1天给予利伐沙班+血塞通注射液至下地活动1周;对照组45例,术后第1天给予利伐沙班至下地活动1周.于术前、术后7~10 d及术后3个月行下肢血管多普勒超声检查,对所有患者的DVT和肺栓塞发生情况进行统计.结果 实验组在观察时间内共出现DVT患者4例(8.89%)显著低于对照组的11例(24.4%)(P<0.05).结论 脊柱术后联合应用利伐沙班与血塞通注射液的抗凝效果要好于单一应用利伐沙班抗凝药.
目的 探討利伐沙班與血塞通註射液聯閤應用對脊柱術後下肢深靜脈血栓(deep venous thrombosis,DVT)的作用.方法 選取2013年5月~2015年5月承德市中心醫院脊柱外科接受脊柱手術治療的患者共90例,隨機分為實驗組和對照組,其中實驗組45例,術後第1天給予利伐沙班+血塞通註射液至下地活動1週;對照組45例,術後第1天給予利伐沙班至下地活動1週.于術前、術後7~10 d及術後3箇月行下肢血管多普勒超聲檢查,對所有患者的DVT和肺栓塞髮生情況進行統計.結果 實驗組在觀察時間內共齣現DVT患者4例(8.89%)顯著低于對照組的11例(24.4%)(P<0.05).結論 脊柱術後聯閤應用利伐沙班與血塞通註射液的抗凝效果要好于單一應用利伐沙班抗凝藥.
목적 탐토리벌사반여혈새통주사액연합응용대척주술후하지심정맥혈전(deep venous thrombosis,DVT)적작용.방법 선취2013년5월~2015년5월승덕시중심의원척주외과접수척주수술치료적환자공90례,수궤분위실험조화대조조,기중실험조45례,술후제1천급여리벌사반+혈새통주사액지하지활동1주;대조조45례,술후제1천급여리벌사반지하지활동1주.우술전、술후7~10 d급술후3개월행하지혈관다보륵초성검사,대소유환자적DVT화폐전새발생정황진행통계.결과 실험조재관찰시간내공출현DVT환자4례(8.89%)현저저우대조조적11례(24.4%)(P<0.05).결론 척주술후연합응용리벌사반여혈새통주사액적항응효과요호우단일응용리벌사반항응약.
Objective To study the effect of the combination of rivaroxaban and Xuesaitong injection on deep venous thrombosis (DVT) of lower extremity after spinal surgery.Methods The clinical data of 90 patients undergoing spinal surgery from May 2013 to May 2015 were retrospective analyzed.The patients were divided into two groups randomly: the treatment group and control group.Forty-five patients in treatment group were treated with rivaroxaban and Xueshuantong injection from 1 st day after surgery to one week after off-bed activity, and forty-five patients in control group were treated with rivaroxaban alone.The vessels of lower extremity were detected by doppler ultrasonography pre-surgery, 7-10d and 3 months post-surgery, then the rates of DVT and pulmonary embolism were statistically analysed.Results The DVT rate in treatment group was 8.89%(4 cases), which was significantly lower than 24.4% (11 cases) in control group (P<0.05).Conclusion The anticogulant effect of the combination of rivaroxaban and Xuesaitong injection is stronger than rivaroxaban alone.
