包头医学院学报
包頭醫學院學報
포두의학원학보
Journal of Baotou Medical College
2015年
11期
32-34
,共3页
失血性休克%全身麻醉%七氟烷%诱导
失血性休剋%全身痳醉%七氟烷%誘導
실혈성휴극%전신마취%칠불완%유도
Hemorrhagic shock%General anesthesia%Sevoflurane%Induction
目的:观察七氟烷吸入诱导与咪唑安定-芬太尼-丙泊酚诱导用于成人失血性休克的血流动力学效果以及不良反应的发生情况. 方法:选择拟行手术的失血性休克患者80例,随机分为观察组和对照组,对照组采用静脉注射咪唑安定-芬太尼-丙泊酚诱导麻醉,观察组吸入7 %七氟烷诱导麻醉,监测并记录两组患者入手术室后诱导前平均动脉压( mean arterial pres-sure,MAP)、心率( heart rate,HR)、诱导期去甲肾上腺素用量、从开始诱导至插管时间,插管前心率、插管后心率等. 统计两组患者诱导期发生不良反应例数. 结果:两组患者的入室后MAP、HR无明显差异( P >0. 05),两组患者诱导至插管时间比较,观察组短于对照组( P <0. 05),两组患者诱导后MAP皆有降低趋势,但对照组维持血压平稳所需血管活性药物去甲肾上腺素用量多于观察组( P <0. 05),两组患者诱导后HR皆有下降趋势,其中插管前心率对照组慢于观察组( P <0. 05),插管后心率对照组与观察组相比无差异( P >0. 05). 结论:七氟烷吸入全麻诱导用于失血性休克患者比咪唑安定-芬太尼-丙泊酚静脉诱导更为安全快速.
目的:觀察七氟烷吸入誘導與咪唑安定-芬太尼-丙泊酚誘導用于成人失血性休剋的血流動力學效果以及不良反應的髮生情況. 方法:選擇擬行手術的失血性休剋患者80例,隨機分為觀察組和對照組,對照組採用靜脈註射咪唑安定-芬太尼-丙泊酚誘導痳醉,觀察組吸入7 %七氟烷誘導痳醉,鑑測併記錄兩組患者入手術室後誘導前平均動脈壓( mean arterial pres-sure,MAP)、心率( heart rate,HR)、誘導期去甲腎上腺素用量、從開始誘導至插管時間,插管前心率、插管後心率等. 統計兩組患者誘導期髮生不良反應例數. 結果:兩組患者的入室後MAP、HR無明顯差異( P >0. 05),兩組患者誘導至插管時間比較,觀察組短于對照組( P <0. 05),兩組患者誘導後MAP皆有降低趨勢,但對照組維持血壓平穩所需血管活性藥物去甲腎上腺素用量多于觀察組( P <0. 05),兩組患者誘導後HR皆有下降趨勢,其中插管前心率對照組慢于觀察組( P <0. 05),插管後心率對照組與觀察組相比無差異( P >0. 05). 結論:七氟烷吸入全痳誘導用于失血性休剋患者比咪唑安定-芬太尼-丙泊酚靜脈誘導更為安全快速.
목적:관찰칠불완흡입유도여미서안정-분태니-병박분유도용우성인실혈성휴극적혈류동역학효과이급불량반응적발생정황. 방법:선택의행수술적실혈성휴극환자80례,수궤분위관찰조화대조조,대조조채용정맥주사미서안정-분태니-병박분유도마취,관찰조흡입7 %칠불완유도마취,감측병기록량조환자입수술실후유도전평균동맥압( mean arterial pres-sure,MAP)、심솔( heart rate,HR)、유도기거갑신상선소용량、종개시유도지삽관시간,삽관전심솔、삽관후심솔등. 통계량조환자유도기발생불량반응례수. 결과:량조환자적입실후MAP、HR무명현차이( P >0. 05),량조환자유도지삽관시간비교,관찰조단우대조조( P <0. 05),량조환자유도후MAP개유강저추세,단대조조유지혈압평은소수혈관활성약물거갑신상선소용량다우관찰조( P <0. 05),량조환자유도후HR개유하강추세,기중삽관전심솔대조조만우관찰조( P <0. 05),삽관후심솔대조조여관찰조상비무차이( P >0. 05). 결론:칠불완흡입전마유도용우실혈성휴극환자비미서안정-분태니-병박분정맥유도경위안전쾌속.
Objective:To observe hemodynamic effects and the occurrence of adverse reactions between sevoflurane inhalation induction and midazolam, fentanyl and propofol intravenous coinduction anesthesia for adult patients with hemorrhagic shock. Methods:80 patients with hemorrhagic shock selected for surgery were randomly divided into the observation group and the control group, the former given inhaled 7%sevoflurane, and the latter given midazolam, fentanyl and propofol intravenous coinduction. Measurements of the mean arterial pressure ( MAP) and heart rate ( HR) were performed in the two groups. During anesthesia induction, the HR of patients before induction and before and after endotracheal intubation were documented, meanwhile, the numbers of adverse reactions cases, doses of norepinephrine, and the duration from the beginning of anesthesia induction to the endotracheal intubation were recorded. And alterations were evaluated by statistical methods. Results:There were no significant differences in HR and MAP before induction between the two groups ( P >0. 05). The duration from the beginning of anesthesia induction to the endotracheal intubation in the observation group was significantly shorter in comparison with that in the control group( P <0. 05). After induction, the MAP of the two groups was inclined to decrease, and the dose of norepinephrine required to maintain blood pressure stable in the control group was more than that of the observation group( P <0. 05). The HR of the two groups had the tendency to incline after induction, and the HR before endotracheal intubation in the control group was slower than that in the observation group, with difference significant( P <0. 05). There was no significant difference in the HR after endotracheal intubation be-tween the two groups( P >0. 05). Conclusion:For patients with hemorrhagic shock, sevoflurane inhalation induction is much safer and fas-ter than midazolam,fentanyl and propofol intravenous coinduction anesthesia.