CAJ | 학술논문

针对仲十二醇的工业生产中会产生大量的副产烷酮的问题,以混合十二烷酮为原料,Ru配合物为催化剂,经催化氢化制备仲十二醇.研究了催化剂用量﹑碱﹑温度﹑氢气压力﹑反应时间对氢化反应的影响,确定了较佳的工艺参数：十二烷酮与催化剂物质的量比为50000：1,叔丁醇钾为十二烷酮摩尔量的1：100,氢气压力3 MPa,反应温度80℃,反应时间10小时.在此条件下,转化率可达99.3%,产物经由红外吸收光谱表征.研究发现,催化剂在循环使用30次时仍具有较高活性,反应条件温和﹑环境友好,适合工业化生产.
침대중십이순적공업생산중회산생대량적부산완동적문제,이혼합십이완동위원료,Ru배합물위최화제,경최화경화제비중십이순.연구료최화제용량﹑감﹑온도﹑경기압력﹑반응시간대경화반응적영향,학정료교가적공예삼수：십이완동여최화제물질적량비위50000：1,숙정순갑위십이완동마이량적1：100,경기압력3 MPa,반응온도80℃,반응시간10소시.재차조건하,전화솔가체99.3%,산물경유홍외흡수광보표정.연구발현,최화제재순배사용30차시잉구유교고활성,반응조건온화﹑배경우호,괄합공업화생산.
Aimed at 1arge amounts of by-product ketones generated in the industria1 preparation process, the secondary dodecano1 was synthesized by cata1ytic hydrogenation using n-dodecanone (n=2-6) as started ma-teria1 and ruthenium comp1ex as cata1yst. The effects of the amount of cata1yst, base, temperature, hydrogen pressure and reaction time on the hydrogenation were investigated.The optimum parameters are obtained at the mo1ar ratio of dodecanone and cata1yst of 50 000:1, the mo1ar ratio of KOtBu and dodecanone of 1:100, hy-drogen pressure of 3 MPa, reaction temperature of 80℃ and reaction time of 10 h. At this condition, the conversion rate of hydrogenation is up to 99.3%. The product was characterized by infrared spectroscopy. The cata1yst sti11 maintain its activation after 30 times recyc1ing, which demonstrated that the method is mi1d, en-vironmenta11y-friend1y and feasib1e to industria1 production .