心血管康复医学杂志
心血管康複醫學雜誌
심혈관강복의학잡지
Chinese Journal of Cardiovascular Rehabilitation Medicine
2015年
6期
627-629
,共3页
胆固醇 , HDL%冠心病%血管成形术 ,气囊 ,冠状动脉
膽固醇 , HDL%冠心病%血管成形術 ,氣囊 ,冠狀動脈
담고순 , HDL%관심병%혈관성형술 ,기낭 ,관상동맥
Cholesterol,HDL%Coronary disease%Angioplasty,balloon,coronary
目的:探讨低水平高密度脂蛋白胆固醇(HDL‐C)对冠心病患者经皮冠状动脉介入术(PCI)后肾脏功能的影响。方法:收集2012年2月至2014年6月来我院救治并行PCI术的冠心病患者300例,依据患者血液中 HDL‐C水平的高低分为正常水平HDL‐C组(179例, HDL‐C≥1.04 mmol/L)与低水平HDL‐C组(121例, HDL‐C<1.04 mmol/L)。比较分析两组患者的基本资料,并应用多因素 Logistic回归分析对PCI术后发生肾损伤的危险因素。结果:与正常水平 HDL‐C 组比较,低水平 HDL‐C 组超重(30.73%比39.67%)、吸烟史(29.05%比41.32%)、心肌梗死史(35.20%比46.28%)、左室射血分数(LVEF )<50%(18.99%比24.79%)、贫血(16.20%比27.27%)及肾损伤(12.85%比22.31%)比例显著升高, P<0.05或<0.01。多因素Logistic回归分析显示年龄、心梗史、贫血、LVEF<50%、糖尿病、对比剂用量及低水平 HDL‐C是冠心病患者PCI术后发生肾损伤的危险因素(β=0.499~1.171, P<0.05或<0.01)。结论:低水平高密度脂蛋白胆固醇是导致冠心病患者PCI术后发生肾功能损伤的危险因素。
目的:探討低水平高密度脂蛋白膽固醇(HDL‐C)對冠心病患者經皮冠狀動脈介入術(PCI)後腎髒功能的影響。方法:收集2012年2月至2014年6月來我院救治併行PCI術的冠心病患者300例,依據患者血液中 HDL‐C水平的高低分為正常水平HDL‐C組(179例, HDL‐C≥1.04 mmol/L)與低水平HDL‐C組(121例, HDL‐C<1.04 mmol/L)。比較分析兩組患者的基本資料,併應用多因素 Logistic迴歸分析對PCI術後髮生腎損傷的危險因素。結果:與正常水平 HDL‐C 組比較,低水平 HDL‐C 組超重(30.73%比39.67%)、吸煙史(29.05%比41.32%)、心肌梗死史(35.20%比46.28%)、左室射血分數(LVEF )<50%(18.99%比24.79%)、貧血(16.20%比27.27%)及腎損傷(12.85%比22.31%)比例顯著升高, P<0.05或<0.01。多因素Logistic迴歸分析顯示年齡、心梗史、貧血、LVEF<50%、糖尿病、對比劑用量及低水平 HDL‐C是冠心病患者PCI術後髮生腎損傷的危險因素(β=0.499~1.171, P<0.05或<0.01)。結論:低水平高密度脂蛋白膽固醇是導緻冠心病患者PCI術後髮生腎功能損傷的危險因素。
목적:탐토저수평고밀도지단백담고순(HDL‐C)대관심병환자경피관상동맥개입술(PCI)후신장공능적영향。방법:수집2012년2월지2014년6월래아원구치병행PCI술적관심병환자300례,의거환자혈액중 HDL‐C수평적고저분위정상수평HDL‐C조(179례, HDL‐C≥1.04 mmol/L)여저수평HDL‐C조(121례, HDL‐C<1.04 mmol/L)。비교분석량조환자적기본자료,병응용다인소 Logistic회귀분석대PCI술후발생신손상적위험인소。결과:여정상수평 HDL‐C 조비교,저수평 HDL‐C 조초중(30.73%비39.67%)、흡연사(29.05%비41.32%)、심기경사사(35.20%비46.28%)、좌실사혈분수(LVEF )<50%(18.99%비24.79%)、빈혈(16.20%비27.27%)급신손상(12.85%비22.31%)비례현저승고, P<0.05혹<0.01。다인소Logistic회귀분석현시년령、심경사、빈혈、LVEF<50%、당뇨병、대비제용량급저수평 HDL‐C시관심병환자PCI술후발생신손상적위험인소(β=0.499~1.171, P<0.05혹<0.01)。결론:저수평고밀도지단백담고순시도치관심병환자PCI술후발생신공능손상적위험인소。
Objective:To explore influence of low high density lipoprotein cholesterol (HDL‐C) level on kidney func‐tion in patients with coronary heart disease (CHD) after percutaneous coronary intervention (PCI) .Methods :A to‐tal of 300 CHD patients ,who were treated and received PCI in our hospital from Feb 2012 to Jun 2014 ,were select‐ed .According to HDL‐C level ,they were divided into normal HDL‐C level group (n=179 ,HDL‐C≥1. 04 mmol/L) and low HDL‐C level group (n= 121 ,HDL‐C< 1.04 mmol/L) .Baseline data were compared between two groups ,and multi‐factor Logistic regression analysis was used to analyze risk factors for kidney injury after PCI .Re‐sults:Compared with normal HDL‐C level group ,there were significant rise in percentages of overweight (30.73%vs .39.67% ) ,smoking history (29.05% vs .41.32% ) ,myocardial infarction history (35.20% vs .46.28% ) ,left ventricular ejection fraction (LVEF) <50% (18.99% vs .24.79% ) ,anemia (16.20% vs .27.27% ) and kidney in‐jury (12. 85% vs .22. 31% ) in low HDL‐C level group , P<0. 05 or <0. 01. Multi‐factor Logistic regression analysis indicated that age ,myocardial infarction history ,anemia ,LVEF<50% ,diabetes mellitus ,dosage of contrast agent and low HDL‐C level were risk factors for kidney injury in CHD patients after PCI (β=0.499~1.171 ,P<0.05 or<0.01) .Conclusion:Low HDL‐C level is a risk factor for renal function injury in CHD patients after PCI .