心血管康复医学杂志
心血管康複醫學雜誌
심혈관강복의학잡지
Chinese Journal of Cardiovascular Rehabilitation Medicine
2015年
6期
603-605
,共3页
王伟红%邓正聪%靳雪芹
王偉紅%鄧正聰%靳雪芹
왕위홍%산정총%근설근
糖尿病 ,2型%血红蛋白A ,糖基化%C反应蛋白质
糖尿病 ,2型%血紅蛋白A ,糖基化%C反應蛋白質
당뇨병 ,2형%혈홍단백A ,당기화%C반응단백질
Diabetes mellitus,type 2%Hemoglobin A,glycosylated%C-reactive protein
目的:研究2型糖尿病患者血糖水平与肱踝脉搏波传导速度(baPWV)及高敏C反应蛋白(hsCRP)水平的关系。方法:选择2型糖尿病患者102例,健康体检者60例(正常对照组)为研究对象,根据糖化血红蛋白水平2型糖尿病患者被分为:HbA1c正常组(44例,HbA1c≤6.5%)和HbA1c升高组(58例,HbA1c>6.5%),检测各组患者的baPWV及血脂、血糖及hsCRP水平,并进行比较。结果:与正常对照组比较,HbA1c正常组和 HbA1c升高组 hsCRP水平[(1.82±0.2) mg/L比(2.7±0.1) mg/L比(3.5±0.1) mg/L]均显著升高,baPWV[(1412±95) cm/s比(1755±72) cm/s比(2040±105) cm/s]显著增加(P均<0.05),且 HbA1c升高组 hsCRP水平和baPWV显著高于 HbA1c正常组(P均<0.05)。结论:2型糖尿病患者肱踝脉搏波传导速度和高敏C反应蛋白水平明显高于正常者,且血糖控制不理想者的明显高于血糖控制理想者的,积极控制患者血糖可延缓动脉粥样硬化进展。
目的:研究2型糖尿病患者血糖水平與肱踝脈搏波傳導速度(baPWV)及高敏C反應蛋白(hsCRP)水平的關繫。方法:選擇2型糖尿病患者102例,健康體檢者60例(正常對照組)為研究對象,根據糖化血紅蛋白水平2型糖尿病患者被分為:HbA1c正常組(44例,HbA1c≤6.5%)和HbA1c升高組(58例,HbA1c>6.5%),檢測各組患者的baPWV及血脂、血糖及hsCRP水平,併進行比較。結果:與正常對照組比較,HbA1c正常組和 HbA1c升高組 hsCRP水平[(1.82±0.2) mg/L比(2.7±0.1) mg/L比(3.5±0.1) mg/L]均顯著升高,baPWV[(1412±95) cm/s比(1755±72) cm/s比(2040±105) cm/s]顯著增加(P均<0.05),且 HbA1c升高組 hsCRP水平和baPWV顯著高于 HbA1c正常組(P均<0.05)。結論:2型糖尿病患者肱踝脈搏波傳導速度和高敏C反應蛋白水平明顯高于正常者,且血糖控製不理想者的明顯高于血糖控製理想者的,積極控製患者血糖可延緩動脈粥樣硬化進展。
목적:연구2형당뇨병환자혈당수평여굉과맥박파전도속도(baPWV)급고민C반응단백(hsCRP)수평적관계。방법:선택2형당뇨병환자102례,건강체검자60례(정상대조조)위연구대상,근거당화혈홍단백수평2형당뇨병환자피분위:HbA1c정상조(44례,HbA1c≤6.5%)화HbA1c승고조(58례,HbA1c>6.5%),검측각조환자적baPWV급혈지、혈당급hsCRP수평,병진행비교。결과:여정상대조조비교,HbA1c정상조화 HbA1c승고조 hsCRP수평[(1.82±0.2) mg/L비(2.7±0.1) mg/L비(3.5±0.1) mg/L]균현저승고,baPWV[(1412±95) cm/s비(1755±72) cm/s비(2040±105) cm/s]현저증가(P균<0.05),차 HbA1c승고조 hsCRP수평화baPWV현저고우 HbA1c정상조(P균<0.05)。결론:2형당뇨병환자굉과맥박파전도속도화고민C반응단백수평명현고우정상자,차혈당공제불이상자적명현고우혈당공제이상자적,적겁공제환자혈당가연완동맥죽양경화진전。
Objective:To study the relationship among brachial ankle pulse wave velocity (baPWV ) ,level of high sensitive C reactive protein (hsCRP ) and blood glucose level in patients with type 2 diabetes mellitus (T2DM ) . Methods :A total of 102 T2DM patients and 60 healthy people undergoing physical examination (normal control group) were selected .According to level of glycosylated hemoglobin (HbA1c) ,T2DM patients were divided into normal HbA1c group (n=44 ,HbA1c≤6. 5% ) and HbA1c elevating group (n=58 ,HbA1c>6. 5% ) .BaPWV ,lev‐els of blood lipids ,blood glucose and hsCRP were measured and compared among above groups .Results:Compared with normal control group ,there were significant rise in hsCRP level [(1.82 ± 0.2) mg/L vs . (2.7 ± 0.1) mg/L vs . (3.5 ± 0.1) mg/L] and baPWV [ (1412 ± 95) cm/s vs . (1755 ± 72) cm/s vs . (2040 ± 105) cm/s] in normal HbA1c group and HbA1c elevating group (P<0.01 all) ,and hsCRP level and baPWV of HbA1c elevating group were sig‐nificantly higher than those of normal HbA1c group ,P<0.05 both .Conclusion:Brachial ankle pulse wave velocity and level of hsCRP of patients with type 2 diabetes mellitus are significantly higher than those of normal subjects , and those of patients with poor blood glucose control are significantly higher than those of patients with good blood glucose control .Active blood glucose control can delay atherosclerosis progress .