当代医药论丛
噹代醫藥論叢
당대의약론총
Contemporary Medicine Forum
2015年
21期
248-250
,共3页
右美托咪定%咪达唑仑%机械通气%连枷胸合并肺损伤%镇静%效果
右美託咪定%咪達唑崙%機械通氣%連枷胸閤併肺損傷%鎮靜%效果
우미탁미정%미체서륜%궤계통기%련가흉합병폐손상%진정%효과
Flail chest and pulmonary injury%dexmedetomidine midazolam
目的:比较用右美托咪定与咪达唑仑对行机械通气的连枷胸合并肺损伤患者进行镇静治疗的临床效果.方法:对2013年1月~2015年1月期间在我院接受机械通气治疗的26例连枷胸合并肺损伤患者的临床资料进行回顾性研究.我院按照随机数表法将这些患者分为对照组和观察组,每组各有13例患者.我院对对照组患者使用咪达唑仑进行镇静治疗,对观察组患者使用右美托咪定进行镇静治疗,然后比较对两组患进行镇静治疗的效果.结果:这两组患者在接受镇静治疗后,观察组患者在心率、平均动脉压的水平以及进行重症监护的时间、进行机械通气的时间、芬太尼的使用量等方面均明显优于对照组患者,差异显著(P<0.05),具有统计学意义.结论:与使用咪达唑仑对行机械通气的连枷胸合并肺损伤患者进行镇静治疗的效果相比,使用右美托咪定对其进行镇静治疗的效果更明显,更值得在临床上推广应用.
目的:比較用右美託咪定與咪達唑崙對行機械通氣的連枷胸閤併肺損傷患者進行鎮靜治療的臨床效果.方法:對2013年1月~2015年1月期間在我院接受機械通氣治療的26例連枷胸閤併肺損傷患者的臨床資料進行迴顧性研究.我院按照隨機數錶法將這些患者分為對照組和觀察組,每組各有13例患者.我院對對照組患者使用咪達唑崙進行鎮靜治療,對觀察組患者使用右美託咪定進行鎮靜治療,然後比較對兩組患進行鎮靜治療的效果.結果:這兩組患者在接受鎮靜治療後,觀察組患者在心率、平均動脈壓的水平以及進行重癥鑑護的時間、進行機械通氣的時間、芬太尼的使用量等方麵均明顯優于對照組患者,差異顯著(P<0.05),具有統計學意義.結論:與使用咪達唑崙對行機械通氣的連枷胸閤併肺損傷患者進行鎮靜治療的效果相比,使用右美託咪定對其進行鎮靜治療的效果更明顯,更值得在臨床上推廣應用.
목적:비교용우미탁미정여미체서륜대행궤계통기적련가흉합병폐손상환자진행진정치료적림상효과.방법:대2013년1월~2015년1월기간재아원접수궤계통기치료적26례련가흉합병폐손상환자적림상자료진행회고성연구.아원안조수궤수표법장저사환자분위대조조화관찰조,매조각유13례환자.아원대대조조환자사용미체서륜진행진정치료,대관찰조환자사용우미탁미정진행진정치료,연후비교대량조환진행진정치료적효과.결과:저량조환자재접수진정치료후,관찰조환자재심솔、평균동맥압적수평이급진행중증감호적시간、진행궤계통기적시간、분태니적사용량등방면균명현우우대조조환자,차이현저(P<0.05),구유통계학의의.결론:여사용미체서륜대행궤계통기적련가흉합병폐손상환자진행진정치료적효과상비,사용우미탁미정대기진행진정치료적효과경명현,경치득재림상상추엄응용.
objective Study of dexmedetomidine in patients with flail chest and pulmonary injury sedative effect.Methods We selected 26 cases of flail chest and pulmonary injury patients, according to the drug use is divided into dexmedetomidine and midazolam group with 13 cases in each group, compared two groups of patients with treatment.Results Dexmedetomidine group after treatment 6 h, 24 h of heart rate and mean arterial pressure were significantly lower than that of midazolam group, with significant difference (P < 0.05); the two groups of patients with 48h heart rate and mean arterial pressure had no significant difference (P > 0.05); the amount of use of dexmedetomidine group ICU patients hospitalization time, offline time and fentanyl were significantly lower than with midazolam group, with significant difference (P < 0.05). 12 cases of dexmedetomidine group out of danger to ordinary ward requirement, slightly more than 9 cases of midazolam group, the difference was not statistically significant (P > 0.05).Conclusion Dexmedetomidine sedation effect is positive, and can enhance the analgesic effect of fentanyl, further reduce dosage, reduce respiratory inhibition, reduce adverse reaction, shorten the duration of hospitalization in ICU and the use of respirator time, worthy of research and application of clinical deepen.
