CAJ | 학술논문

脂蛋白肾病是以蛋白尿、肾功能损伤和脂蛋白代谢异常为主要表现的一种罕见疾病，主要发病机制是载脂蛋白 E 基因突变。脂蛋白肾病的发病率尚不清楚。本文总结了脂蛋白肾病的病理生理机制、临床及病理表现、诊断及鉴别诊断，以及当前可能有效的治疗手段。
지단백신병시이단백뇨、신공능손상화지단백대사이상위주요표현적일충한견질병，주요발병궤제시재지단백 E 기인돌변。지단백신병적발병솔상불청초。본문총결료지단백신병적병리생리궤제、림상급병리표현、진단급감별진단，이급당전가능유효적치료수단。
Lipoprotein glomerulopathy is a rare disease characterized by proteinuria,renal function insufficiency,and lipoprotein metabolism dysfunction.The main pathogenesis of the disease is apolipoprotein E (apoE)gene mutation.Lipoprotein glomerulopathy is a rare ridney disease,with its incidence being unknown.This article summarizes the pathophysiology,clinical and pathological manifestations,diagnosis and differential diagnosis of lipoprotein glomerulopathy,as well as the potential effective treatments.