中国药业
中國藥業
중국약업
China Pharmaceuticals
2015年
21期
240-241
,共2页
重组活性Ⅶ因子%综合护理干预%产后大出血
重組活性Ⅶ因子%綜閤護理榦預%產後大齣血
중조활성Ⅶ인자%종합호리간예%산후대출혈
Recombinant Activated Factor Ⅶ%comprehensive nursing intervention%postpartum hemorrhage
目的 观察重组活性Ⅶ因子联合综合护理干预对产后大出血产妇的临床效果.方法 选取104例产后大出血患者,根据随机数字表法分为对照组和观察组,各52例.对照组采用常规止血及常规护理干预,观察组采用重组活性Ⅶ因子联合综合护理干预.结果 观察组总有效率显著高于对照组( P<0. 05),护理总满意率显著高于对照组( P<0. 05),总出血量、止血时间及住院时间均显著短于对照组( P<0. 05);与对照组相比,观察组凝血酶原时间( PT )及 D-二聚体明显减少,而纤维蛋白原( FIB )显著增多( P<0. 05),两组间活化部分凝血活酶时间( APTT )未见明显变化( P>0. 05).结论 重组活性Ⅶ因子联合综合护理干预治疗产后大出血疗效显著,可明显缩短止血时间及住院时间,且无明显不良反应发生,安全可靠,值得推广.
目的 觀察重組活性Ⅶ因子聯閤綜閤護理榦預對產後大齣血產婦的臨床效果.方法 選取104例產後大齣血患者,根據隨機數字錶法分為對照組和觀察組,各52例.對照組採用常規止血及常規護理榦預,觀察組採用重組活性Ⅶ因子聯閤綜閤護理榦預.結果 觀察組總有效率顯著高于對照組( P<0. 05),護理總滿意率顯著高于對照組( P<0. 05),總齣血量、止血時間及住院時間均顯著短于對照組( P<0. 05);與對照組相比,觀察組凝血酶原時間( PT )及 D-二聚體明顯減少,而纖維蛋白原( FIB )顯著增多( P<0. 05),兩組間活化部分凝血活酶時間( APTT )未見明顯變化( P>0. 05).結論 重組活性Ⅶ因子聯閤綜閤護理榦預治療產後大齣血療效顯著,可明顯縮短止血時間及住院時間,且無明顯不良反應髮生,安全可靠,值得推廣.
목적 관찰중조활성Ⅶ인자연합종합호리간예대산후대출혈산부적림상효과.방법 선취104례산후대출혈환자,근거수궤수자표법분위대조조화관찰조,각52례.대조조채용상규지혈급상규호리간예,관찰조채용중조활성Ⅶ인자연합종합호리간예.결과 관찰조총유효솔현저고우대조조( P<0. 05),호리총만의솔현저고우대조조( P<0. 05),총출혈량、지혈시간급주원시간균현저단우대조조( P<0. 05);여대조조상비,관찰조응혈매원시간( PT )급 D-이취체명현감소,이섬유단백원( FIB )현저증다( P<0. 05),량조간활화부분응혈활매시간( APTT )미견명현변화( P>0. 05).결론 중조활성Ⅶ인자연합종합호리간예치료산후대출혈료효현저,가명현축단지혈시간급주원시간,차무명현불량반응발생,안전가고,치득추엄.
Objective To investigate the efficacy of the Recombinant Activated Factor Ⅶ combined with comprehensive nursing interven-tion in treating postpartum hemorrhage. Methods 104 cases of postpartum hemorrhage were randomly divided into the control group ( n=52 ) and the observation group ( n=52 ) based on the random number table. The control group received conventional hemostatic therapy and routine nursing intervention;the observation group used Recombinant Activated Factor Ⅶ and comprehensive nursing inter-vention. The total efficiency of hemostasis, nursing satisfaction, bleeding time and hospitalization time and safety evaluation were compared between the two groups. Results The total effective rate of the observation group was significantly higher than the control group ( P <0. 05);the satisfaction rate of the observation group was significantly higher than the control group ( P < 0. 05 );the hemostasis volume, bleed-ing time and hospitalization time of the observation group were significantly less than those of the control group ( P < 0. 05 );compared with the control group, the decrease of PT and D-dimer in the observation group were more obvious, while the increase of FIB was more obvious than ( P < 0. 05 ) . The APTT of the two groups had no significant changes ( P > 0. 05 ) . Conclusion Recombinant Acti-vated Factor Ⅶ combined with comprehensive nursing intervention has significant efficacy in treating postpartum hemorrhage, can signifi-cantly shorten the bleeding time and hospitalization time, and is safe and reliable with no significant adverse events, and thus has im-portant clinical research value.
