中国药业
中國藥業
중국약업
China Pharmaceuticals
2015年
21期
89-90
,共2页
郑吉卫%朱琼%柳德洪%别世杰%亢留玉
鄭吉衛%硃瓊%柳德洪%彆世傑%亢留玉
정길위%주경%류덕홍%별세걸%항류옥
扁桃体切除术%全身麻醉%地佐辛%苏醒期躁动
扁桃體切除術%全身痳醉%地佐辛%囌醒期躁動
편도체절제술%전신마취%지좌신%소성기조동
tonsillectomy%general anesthesia%dezocine%agitation during awakening period
目的 探讨在扁桃体切除术全身麻醉中,采用不同剂量地佐辛对患者苏醒期的影响.方法 选取2013年6月至2015年1月确诊并接受扁桃体切除术的患者 120 例,按随机数字表法将患者进行分组,A 组患者给予 0. 05 mg/kg 的地佐辛滴注,B组患者给予0. 1 mg/kg的地佐辛滴注,C组患者给予0. 2 mg/kg的地佐辛滴注.结果 A组、B组在恢复呼吸时间、苏醒时间及拔出气管导管时间上无显著性差异( P>0. 05),与C组相比具有显著性差异( P<0. 05);C组患者的躁动评分(1. 64 ± 0. 53)分和疼痛评分(1. 85 ± 0. 63)分,显著低于A组的(2. 65 ± 0. 84)分和(5. 21 ± 1. 73)分( P <0. 05);3 组恶心呕吐、心动过缓、呼吸困难及睡眠过度发生率等临床不良反应相比,无显著性差异( P >0. 05).结论 地佐辛在扁桃体切除术中具有一定的抗躁动和抗疼痛作用,但不同剂量的作用效果具有一定差异,0. 1 mg/kg的滴注量更安全、有效.
目的 探討在扁桃體切除術全身痳醉中,採用不同劑量地佐辛對患者囌醒期的影響.方法 選取2013年6月至2015年1月確診併接受扁桃體切除術的患者 120 例,按隨機數字錶法將患者進行分組,A 組患者給予 0. 05 mg/kg 的地佐辛滴註,B組患者給予0. 1 mg/kg的地佐辛滴註,C組患者給予0. 2 mg/kg的地佐辛滴註.結果 A組、B組在恢複呼吸時間、囌醒時間及拔齣氣管導管時間上無顯著性差異( P>0. 05),與C組相比具有顯著性差異( P<0. 05);C組患者的躁動評分(1. 64 ± 0. 53)分和疼痛評分(1. 85 ± 0. 63)分,顯著低于A組的(2. 65 ± 0. 84)分和(5. 21 ± 1. 73)分( P <0. 05);3 組噁心嘔吐、心動過緩、呼吸睏難及睡眠過度髮生率等臨床不良反應相比,無顯著性差異( P >0. 05).結論 地佐辛在扁桃體切除術中具有一定的抗躁動和抗疼痛作用,但不同劑量的作用效果具有一定差異,0. 1 mg/kg的滴註量更安全、有效.
목적 탐토재편도체절제술전신마취중,채용불동제량지좌신대환자소성기적영향.방법 선취2013년6월지2015년1월학진병접수편도체절제술적환자 120 례,안수궤수자표법장환자진행분조,A 조환자급여 0. 05 mg/kg 적지좌신적주,B조환자급여0. 1 mg/kg적지좌신적주,C조환자급여0. 2 mg/kg적지좌신적주.결과 A조、B조재회복호흡시간、소성시간급발출기관도관시간상무현저성차이( P>0. 05),여C조상비구유현저성차이( P<0. 05);C조환자적조동평분(1. 64 ± 0. 53)분화동통평분(1. 85 ± 0. 63)분,현저저우A조적(2. 65 ± 0. 84)분화(5. 21 ± 1. 73)분( P <0. 05);3 조악심구토、심동과완、호흡곤난급수면과도발생솔등림상불량반응상비,무현저성차이( P >0. 05).결론 지좌신재편도체절제술중구유일정적항조동화항동통작용,단불동제량적작용효과구유일정차이,0. 1 mg/kg적적주량경안전、유효.
Objective To investigate the effect of different doses of dezocine on agitation during analepsia period of tonsillectomy with general anesthesia. Methods 120 cases of patients from June 2013 to January 2015 in the hospital who performed tonsillectomy were divided according to the random number table method. The group A was given dezocine drops 0. 05 mg/kg, the group B 0. 1 mg/kg, the group C of 0. 2 mg/kg. Results The recovery of respiratory time, awakening time and extubation time in group A and B had no significant difference, and had statistical difference compared with group C ( P < 0. 05 );the agitation score of the group C was ( 1. 64 ± 0. 53 ) and the pain score was ( 1. 85 ± 0. 63 ) , which were significantly lower than ( 2. 65 ± 0. 84 ) and ( 5. 21 ± 1. 73 ) of group A;the adverse reaction of nausea and retching, heartbeat bradycardia, difficulty breathing and sleep over of the three groups had no significant difference ( P < 0. 05 ) . Conclusion Dezocine has certain anti agitation and anti pain effect in tonsillectomy, but the effects and adverse reactions of different dose have some differences;the application amount of 0. 1mg/kg in the clinical infusion during general anesthesia is more safe and effective.
