CAJ | 학술논문

目的考察都梁软胶囊联合其他药物治疗偏头痛的临床疗效.方法检索中国知网期刊数据库,关键词"都梁软胶囊""头痛",检索时间1999年至2015年,提取符合联合用药治疗偏头痛纳入标准的文献数据,运用Revman 5. 3版软件进行Meta分析.结果共检索到99条结果,最终纳入6篇文献.都梁软胶囊联合其他药物(尼莫地平或氟桂利嗪)治疗偏头痛共258例,对照组247例.Meta分析结果显示,都梁软胶囊联合其他药物能有效治疗偏头痛[ OR=0. 27,95% CI(0. 16,0. 44)] ,有效率分别为(90. 6 ± 2. 3)%和(71. 3 ± 4. 4)%( P<0. 01).结论都梁软胶囊与其他药物(如尼莫地平、氟桂利嗪等)联用治疗偏头痛,能显著增强临床疗效.
목적 고찰도량연효낭연합기타약물치료편두통적림상료효.방법 검색중국지망기간수거고,관건사"도량연효낭""두통",검색시간1999년지2015년,제취부합연합용약치료편두통납입표준적문헌수거,운용Revman 5. 3판연건진행Meta분석.결과 공검색도99조결과,최종납입6편문헌.도량연효낭연합기타약물(니막지평혹불계리진)치료편두통공258례,대조조247례.Meta분석결과현시,도량연효낭연합기타약물능유효치료편두통[ OR=0. 27,95% CI(0. 16,0. 44)] ,유효솔분별위(90. 6 ± 2. 3)%화(71. 3 ± 4. 4)%( P<0. 01).결론 도량연효낭여기타약물(여니막지평、불계리진등)련용치료편두통,능현저증강림상료효.
Objective To explore clinical efficacy of combining Douliang Soft Capsules with others drugs on migraine. Methods Search-ing CNKI database with typing keywords"Douliang Soft Capsules"and"migraine"from 1999 to June 20th, 2015. Data from included publications with the treatment of migraine with combining Douliang Soft Capsules were meta analyzed by Revman 5. 3 software. Results 6 pubilications were included from 99 retrieved results. 258 cases with migraine were orally given combined therapy with Douliang Soft Capsules and other drugs ( nimodipine or flunarizine ) , while 247 patients as the control group. Meta analysis reveals that combination of Douliang Soft Capsules with other drugs can effectively improve the symptoms of migraine [ OR=0. 27, 95% CI ( 0. 16, 0. 44 ) ] . The effectiveness was ( 90. 6 ± 2. 3 )% and ( 71. 3 ± 4. 4 )% , respectively ( P < 0. 01 ) . Conclusion Combination of Douliang Soft Capsules with other drugs ( eg. nimodipine, flunarizine, etc ) can significantly increases the clinical efficacy in patients with migraine.