中国药业
中國藥業
중국약업
China Pharmaceuticals
2015年
21期
143-146
,共4页
徐彬%杨忠英%樊洪忠%姜云达
徐彬%楊忠英%樊洪忠%薑雲達
서빈%양충영%번홍충%강운체
社区获得性肺炎%药物利用评价%药物利用评估%药物利用指数
社區穫得性肺炎%藥物利用評價%藥物利用評估%藥物利用指數
사구획득성폐염%약물이용평개%약물이용평고%약물이용지수
community-acquired pneumonnia%drug utilization review%drug use evaluation%drug utilization index
目的 评价医院纳入临床路径的社区获得性肺炎( CAP )患者抗菌药物使用合理性.方法 采用药物利用评价( DUR )和药物利用评估( DUE )法分析某院呼吸科2014年出院的202例纳入临床路径的CAP患者抗菌药物使用情况、治疗过程监测、临床治疗结果.结果 纳入DUR分析的抗菌药物共12种,其中7种药物利用指数( DUI ) <1,2种DUI=1,3种DUI>1;DUE结果显示,所有患者都进行了疾病严重程度评估,对异常血常规、肝功能、肾功能、C反应蛋白、降钙素原、血沉、血钾、病原学检查结果、影像学检查结果等复查的比例分别为81. 43%,60. 00%,64. 29%,44. 85%,62. 16%,18. 44%,100. 00%,83. 33%,61. 73%.用药频度( DDDs )居前4位的抗菌药物分别为注射用头孢呋辛钠、左氧氟沙星注射液、注射用乳酸阿奇霉素、注射用头孢替安.结论 医院纳入临床路径的CAP患者抗菌药物的使用仍需加强用药过程监测.联合应用DUR和DUE法可更全面地评价CAP患者的用药情况.
目的 評價醫院納入臨床路徑的社區穫得性肺炎( CAP )患者抗菌藥物使用閤理性.方法 採用藥物利用評價( DUR )和藥物利用評估( DUE )法分析某院呼吸科2014年齣院的202例納入臨床路徑的CAP患者抗菌藥物使用情況、治療過程鑑測、臨床治療結果.結果 納入DUR分析的抗菌藥物共12種,其中7種藥物利用指數( DUI ) <1,2種DUI=1,3種DUI>1;DUE結果顯示,所有患者都進行瞭疾病嚴重程度評估,對異常血常規、肝功能、腎功能、C反應蛋白、降鈣素原、血沉、血鉀、病原學檢查結果、影像學檢查結果等複查的比例分彆為81. 43%,60. 00%,64. 29%,44. 85%,62. 16%,18. 44%,100. 00%,83. 33%,61. 73%.用藥頻度( DDDs )居前4位的抗菌藥物分彆為註射用頭孢呋辛鈉、左氧氟沙星註射液、註射用乳痠阿奇黴素、註射用頭孢替安.結論 醫院納入臨床路徑的CAP患者抗菌藥物的使用仍需加彊用藥過程鑑測.聯閤應用DUR和DUE法可更全麵地評價CAP患者的用藥情況.
목적 평개의원납입림상로경적사구획득성폐염( CAP )환자항균약물사용합이성.방법 채용약물이용평개( DUR )화약물이용평고( DUE )법분석모원호흡과2014년출원적202례납입림상로경적CAP환자항균약물사용정황、치료과정감측、림상치료결과.결과 납입DUR분석적항균약물공12충,기중7충약물이용지수( DUI ) <1,2충DUI=1,3충DUI>1;DUE결과현시,소유환자도진행료질병엄중정도평고,대이상혈상규、간공능、신공능、C반응단백、강개소원、혈침、혈갑、병원학검사결과、영상학검사결과등복사적비례분별위81. 43%,60. 00%,64. 29%,44. 85%,62. 16%,18. 44%,100. 00%,83. 33%,61. 73%.용약빈도( DDDs )거전4위적항균약물분별위주사용두포부신납、좌양불사성주사액、주사용유산아기매소、주사용두포체안.결론 의원납입림상로경적CAP환자항균약물적사용잉수가강용약과정감측.연합응용DUR화DUE법가경전면지평개CAP환자적용약정황.
Objective To evaluate the rationality of the drug utilization in patients with CAP in the hospital. Methods The drug uti-lization and treatment of 202 patients with CAP in our hospital collected in 2014 was analyzed entirely by DUR and DUE. Results Among the 12 kinds of drugs involved in 202 patients, values of DUI of 3 kinds of drugs were more than 1, while values of DUI of other 9 kinds of drugs were less than 1 or equal to 1, and all the patients underwent the blood routine detection and evaluation of liv-er and kidney function to monitor the severity of the disease. During the therapeutic process, the monitoring percentages of abnormal blood routine detection, liver function, kidney function, CRP, procalcitonin, erythrocyte sedimentation rate, potassium levels, pathogen and im-ageological examination were 81. 43%, 60. 00%, 64. 29%, 44. 85%, 62. 16%, 18. 44%, 100. 00%, 83. 33%, 61. 73%, respectively. The top 4 drugs in terms of drug use frequency were Cefuroxime Sodium, Levofloxacin Injection, Azithromycinfor Injection, Cefotiam Hydrochloride for Injection. Conclusion The supervision of antibacterial drugs utilization in patients in our hospital still is enhanced. A more compre-hensive evaluation of drug utilization in patients with CAP can be achieved by using DUR plus DUE method.
