中国小儿急救医学
中國小兒急救醫學
중국소인급구의학
Chinese Pediatric Emergency Medicine
2015年
11期
791-794
,共4页
脓毒症%肾上腺功能不全%发病机制%皮质醇
膿毒癥%腎上腺功能不全%髮病機製%皮質醇
농독증%신상선공능불전%발병궤제%피질순
Sepsis%Adrenal insufficiency%Mechanism%Steroid
脓毒症特别是脓毒性休克可继发肾上腺功能障碍.炎症介质、凝血功能障碍、皮质醇代谢异常或糖皮质激素抵抗等与肾上腺功能障碍发病密切相关.虽然脓毒症相关性肾上腺功能障碍已逐步得到医务人员的重视,但其发病机制尚未明确,本文就脓毒症相关性肾上腺功能障碍的发病机制作一综述.
膿毒癥特彆是膿毒性休剋可繼髮腎上腺功能障礙.炎癥介質、凝血功能障礙、皮質醇代謝異常或糖皮質激素牴抗等與腎上腺功能障礙髮病密切相關.雖然膿毒癥相關性腎上腺功能障礙已逐步得到醫務人員的重視,但其髮病機製尚未明確,本文就膿毒癥相關性腎上腺功能障礙的髮病機製作一綜述.
농독증특별시농독성휴극가계발신상선공능장애.염증개질、응혈공능장애、피질순대사이상혹당피질격소저항등여신상선공능장애발병밀절상관.수연농독증상관성신상선공능장애이축보득도의무인원적중시,단기발병궤제상미명학,본문취농독증상관성신상선공능장애적발병궤제작일종술.
Adrenal insufficiency is a common complication in sepsis patients, with a higher morbidity in septic shock patients.Adrenal insufficiency is closely related to coagulation disorders, inflammatory mediators and glucocorticoid resistance.The mechanisms of adrenal insufficiency in sepsis have not been discussed clearly.In the present review we detail the mechanisms of adrenal insufficiency that are active during sepsis.