中国小儿急救医学
中國小兒急救醫學
중국소인급구의학
Chinese Pediatric Emergency Medicine
2015年
11期
804-806
,共3页
急性肺损伤%肺泡巨噬细胞%凋亡%趋化因子
急性肺損傷%肺泡巨噬細胞%凋亡%趨化因子
급성폐손상%폐포거서세포%조망%추화인자
Acute lung injury%Alveolar macrophage%Apoptosis%Chemotactic factor
小儿急性肺损伤(acute lung injury,ALI)是以肺毛细血管通透性增加为特征的临床综合征,急性呼吸窘迫综合征是其更严重的表现,是小儿最常见的危重症之一.肺泡巨噬细胞是肺部防御病原微生物和肺损伤的第一道防线,越来越多的证据表明,其在ALI的发生、发展及转归中发挥重要作用.近年来,肺泡巨噬细胞在ALI中的作用受到了广泛的关注.本文就近年来肺泡巨噬细胞在ALI中作用的研究进展作一综述.
小兒急性肺損傷(acute lung injury,ALI)是以肺毛細血管通透性增加為特徵的臨床綜閤徵,急性呼吸窘迫綜閤徵是其更嚴重的錶現,是小兒最常見的危重癥之一.肺泡巨噬細胞是肺部防禦病原微生物和肺損傷的第一道防線,越來越多的證據錶明,其在ALI的髮生、髮展及轉歸中髮揮重要作用.近年來,肺泡巨噬細胞在ALI中的作用受到瞭廣汎的關註.本文就近年來肺泡巨噬細胞在ALI中作用的研究進展作一綜述.
소인급성폐손상(acute lung injury,ALI)시이폐모세혈관통투성증가위특정적림상종합정,급성호흡군박종합정시기경엄중적표현,시소인최상견적위중증지일.폐포거서세포시폐부방어병원미생물화폐손상적제일도방선,월래월다적증거표명,기재ALI적발생、발전급전귀중발휘중요작용.근년래,폐포거서세포재ALI중적작용수도료엄범적관주.본문취근년래폐포거서세포재ALI중작용적연구진전작일종술.
Acute lung injury (ALI) is a kind of clinical syndrome which is characterized by the rising on capillary permeability.Acute respiratory distress syndrome(ARDS) is a serious kind of manifestation of ALI and also a usual kind of critical illness in children.Alveolar macrophage is the first defense line against pathogenic microorganisms and lung injury.More and more evidences show that it plays an important role during the period of occurrence, development and prognosis in ALI.In the last few years, there is an extensive focus on the effect of alveolar macrophage in ALI.This summarization makes a general review on the recent research progress of the effect of alveolar macrophages in ALI.
