中国综合临床
中國綜閤臨床
중국종합림상
Clinical Medicine of China
2015年
12期
1079-1082
,共4页
嗜酸性粒细胞%急性心肌梗死%白细胞%肌钙蛋白Ⅰ
嗜痠性粒細胞%急性心肌梗死%白細胞%肌鈣蛋白Ⅰ
기산성립세포%급성심기경사%백세포%기개단백Ⅰ
Eosinophils%Acute myocardial infarction%Leukocyte%Troponin Ⅰ
目的 观察急性心肌梗死(AMI)患者外周血嗜酸性粒细胞(EOS)数量的变化,探讨外周血EOS水平与AMI的关系.方法 选择北京天坛医院2014年1月至2014年7月入院治疗的AMI患者50例,包括23例急性非ST段抬高型心肌梗死(NSTEMI)和27例急性ST段抬高型心肌梗死(STEMI);选择同期北京天坛医院体检中心体检者50名作为对照组.测定所有入组者外周血白细胞(leukocyte,WBC)数量、EOS数量和百分比、肌钙蛋白Ⅰ,观察两组间外周血WBC数量、EOS数量和百分比的差别,在AMI组采用Pearson相关分析法分析EOS与肌钙蛋白Ⅰ的相关性.结果 AMI组患者外周血EO5计数(0.02±0.01) ×109/L,EOS百分比(0.40±0.49)％,与对照组外周血EOS计数(0.24±0.14)× 109/L,EOS百分比(1.25±0.54)％,比较差异均有统计学意义(t=11.083,P＜0.01;t=8.242,P＜0.01).在AMI组中,EOS数量及百分比和肌酐蛋白Ⅰ之间有显著的负相关(r值分别为-0.390、-0.387,P均＜0.05).结论 AMI患者外周血EOS数量明显减少,EOS和肌钙蛋白Ⅰ之间存在负相关,EOS与AMI密切相关.
目的 觀察急性心肌梗死(AMI)患者外週血嗜痠性粒細胞(EOS)數量的變化,探討外週血EOS水平與AMI的關繫.方法 選擇北京天罈醫院2014年1月至2014年7月入院治療的AMI患者50例,包括23例急性非ST段抬高型心肌梗死(NSTEMI)和27例急性ST段抬高型心肌梗死(STEMI);選擇同期北京天罈醫院體檢中心體檢者50名作為對照組.測定所有入組者外週血白細胞(leukocyte,WBC)數量、EOS數量和百分比、肌鈣蛋白Ⅰ,觀察兩組間外週血WBC數量、EOS數量和百分比的差彆,在AMI組採用Pearson相關分析法分析EOS與肌鈣蛋白Ⅰ的相關性.結果 AMI組患者外週血EO5計數(0.02±0.01) ×109/L,EOS百分比(0.40±0.49)％,與對照組外週血EOS計數(0.24±0.14)× 109/L,EOS百分比(1.25±0.54)％,比較差異均有統計學意義(t=11.083,P＜0.01;t=8.242,P＜0.01).在AMI組中,EOS數量及百分比和肌酐蛋白Ⅰ之間有顯著的負相關(r值分彆為-0.390、-0.387,P均＜0.05).結論 AMI患者外週血EOS數量明顯減少,EOS和肌鈣蛋白Ⅰ之間存在負相關,EOS與AMI密切相關.
목적 관찰급성심기경사(AMI)환자외주혈기산성립세포(EOS)수량적변화,탐토외주혈EOS수평여AMI적관계.방법 선택북경천단의원2014년1월지2014년7월입원치료적AMI환자50례,포괄23례급성비ST단태고형심기경사(NSTEMI)화27례급성ST단태고형심기경사(STEMI);선택동기북경천단의원체검중심체검자50명작위대조조.측정소유입조자외주혈백세포(leukocyte,WBC)수량、EOS수량화백분비、기개단백Ⅰ,관찰량조간외주혈WBC수량、EOS수량화백분비적차별,재AMI조채용Pearson상관분석법분석EOS여기개단백Ⅰ적상관성.결과 AMI조환자외주혈EO5계수(0.02±0.01) ×109/L,EOS백분비(0.40±0.49)％,여대조조외주혈EOS계수(0.24±0.14)× 109/L,EOS백분비(1.25±0.54)％,비교차이균유통계학의의(t=11.083,P＜0.01;t=8.242,P＜0.01).재AMI조중,EOS수량급백분비화기항단백Ⅰ지간유현저적부상관(r치분별위-0.390、-0.387,P균＜0.05).결론 AMI환자외주혈EOS수량명현감소,EOS화기개단백Ⅰ지간존재부상관,EOS여AMI밀절상관.
Objective To observe the changes of eosinophils (EOS) in peripheral blood in patients with acute myocardial infarction (AMI).To investingate the association of EOS in peripheral blood and acute myocardial infarction.Methods The single-centre study enrolled 50 acute myocardial infarction patients (23 cases were NSTEMI and 27 cases were STEMI) who were treated in Beijing Tiantan Hospital from January 2014 to July 2014.Fifty medical individuals who were randomly chosen from the same period of time.White blood cell counts,EOS counts and percentages, levels of Troponin Ⅰ of all individuals were determined.Compare White blood cell counts,EOS counts and percentages between two groups.Association of EOS in peripheral blood and Troponin Ⅰ in patients with acute myocardial infarction was evaluated by Pearson correlation.Results The levels of eosinophils counts ((0.02±0.01) × 109/L vs.(0.24±0.14) × 109/L) and percentages ((0.40±0.49) ％ vs.(1.25±0.54)％) in AMI patients were significantly lower than those in the control group (t =11.083, P＜0.01;t=8.242,P＜0.01).There was significant inverse correlation between EOS counts and percentage and levels of Troponin Ⅰ(r=-0.390,-0.387;P＜0.05).Conclusion Patients with acute myocardial infarction presented decreased eosinophils counts and percentages.EOS counts and percentage and levels of Troponin Ⅰ presented negative correlation.It was close relation of EOS and acute myocardial infarction.
