CAJ | 학술논문

目的探讨转换控制器介导的cool-tip内冷循环多电极同步射频消融与常规单电极重叠消融在离体牛肝消融效果的差异.方法采用电极裸露端长度为3、4 cm的多电极同步射频消融与常规单电极重叠射频消融离体牛肝,观察两种方法消融灶的形态特征,测量并比较消融灶大小差异.结果两种方法形成的消融灶均呈椭球形.转换控制器介导的4 cm裸露端多电极同步射频消融16 min的消融灶纵径、横径、电极前端消融长度、体积分别为(7.12±0.52) cm、(5.71±0.47) cm、(1.77±0.29) cm、(102±20) cm3,均＞常规4 cin裸露端单电极重叠射频消融36 min的消融灶大小(均P＜0.01).在相同的16 min消融时间内,转换器介导的4 cm裸露端电极产生的消融灶纵径和体积明显＞3 cm裸露端电极产生的消融灶(均P＜0.01);但两者的横径和电极前端消融长度差异无统计学意义(均P＞0.05).结论与常规单电极重叠射频消融相比,转换控制器介导的多电极同步射频消融能在更短的时间内产生更大的消融范围,这可以为临床大肝癌消融治疗提供新的尝试.
목적 탐토전환공제기개도적cool-tip내랭순배다전겁동보사빈소융여상규단전겁중첩소융재리체우간소융효과적차이.방법 채용전겁라로단장도위3、4 cm적다전겁동보사빈소융여상규단전겁중첩사빈소융리체우간,관찰량충방법소융조적형태특정,측량병비교소융조대소차이.결과 량충방법형성적소융조균정타구형.전환공제기개도적4 cm라로단다전겁동보사빈소융16 min적소융조종경、횡경、전겁전단소융장도、체적분별위(7.12±0.52) cm、(5.71±0.47) cm、(1.77±0.29) cm、(102±20) cm3,균＞상규4 cin라로단단전겁중첩사빈소융36 min적소융조대소(균P＜0.01).재상동적16 min소융시간내,전환기개도적4 cm라로단전겁산생적소융조종경화체적명현＞3 cm라로단전겁산생적소융조(균P＜0.01);단량자적횡경화전겁전단소융장도차이무통계학의의(균P＞0.05).결론 여상규단전겁중첩사빈소융상비,전환공제기개도적다전겁동보사빈소융능재경단적시간내산생경대적소융범위,저가이위림상대간암소융치료제공신적상시.
Objective To explore the different effects in ex vivo bovine liver between multiple cooltip internally cooled electrodes synchronous radiofrequency ablation via switching controller and conventional single electrode overlapping radiofrequency ablation.Method The above two methods were used to ablate in ex vivo bovine liver respectively.Electrode exposed end was 3 cm or 4 cm in length.The morphological characteristics of lesions created by two methods were observed, the sizes of the ablated lesions were measured and compared.Result The formation of lesions ablated by both two methods was ellipsoidal.The longitudinal diameter, transverse diameter, front-end diameter and volume of the lesions ablated 16 mins by multi-electrode synchronous radiofrequency ablation via switching controller were (7.12 ± 0.52) cm, (5.71 ±0.47) cm, (1.77 ±0.29) cm, (102 ±20) cm3 ,respectively.All of them are larger than the lesions ablated 36 mins by conventional single electrode overlapping radiofrequency ablation(P ＜ 0.01).At the same 16 mins, multi-electrode synchronous radiofrequency ablation via switching controller created longer longitudinal diameter and large volume(P ＜ 0.01) with longer exposed end electrodes(4 cm vs 3 cm).But the transverse diameter, the front-end diameter had no statistical difference (P ＞ 0.05).Conclusion Compared with the conventional single electrode overlapping radiofrequency ablation, multi-electrode synchronous radiofrequency ablation via switching controller create larger lesion in the shorter time.It may provide a new attempt for the clinical treatment of large hepatocellular carcinoma.