CAJ | 학술논문

钙卫蛋白是S100蛋白家族中的一种钙、锌结合蛋白,由中性粒细胞表达,具有重要的细胞外功能.该文综述了粪便钙卫蛋白在肠道病理状态下如炎症性肠病、肠道肿瘤、坏死性小肠结肠炎、过敏相关性肠病等疾病的变化,以及对这类疾病在诊断、复发的评估及治疗的反应程度上的应用价值.
개위단백시S100단백가족중적일충개、자결합단백,유중성립세포표체,구유중요적세포외공능.해문종술료분편개위단백재장도병리상태하여염증성장병、장도종류、배사성소장결장염、과민상관성장병등질병적변화,이급대저류질병재진단、복발적평고급치료적반응정도상적응용개치.
Calprotectin is a calcium-and zinc-binding protein of the S100 family expressed mainly by neutrophils with important extracellular activity.This paper reviews current findings about the implication of faecal calprotectin in the diagnosis, follow-up, assessment of relapses, and response to treatment in intestinaldiseases, such as inflammatory bowel disease, intestinal tumor, necrotizing enterocolitis, allergy and intestinal infection.