CAJ | 학술논문

硒是人、动物和某些微生物正常生存所必需的一种非金属微量元素.硒对生物健康具有双向作用,即氧化作用和抗氧化作用.缺硒可能引发免疫系统功能损伤,导致一些病毒感染毒性增强或感染加剧,以及体内谷胱甘肽过氧化物酶活性下降,增加了氧化损伤和病毒基因突变的可能性.硒的安全摄取量范围相对较窄,过量的摄取可能导致中毒.该文就硒对生物健康双向作用的研究进展作一综述.
서시인、동물화모사미생물정상생존소필수적일충비금속미량원소.서대생물건강구유쌍향작용,즉양화작용화항양화작용.결서가능인발면역계통공능손상,도치일사병독감염독성증강혹감염가극,이급체내곡광감태과양화물매활성하강,증가료양화손상화병독기인돌변적가능성.서적안전섭취량범위상대교착,과량적섭취가능도치중독.해문취서대생물건강쌍향작용적연구진전작일종술.
Selenium, a metalloid mineral micronutrient,is an essential component for the adequate and healthy life of human, animals, and some other microorganisms.Selenium has antioxidative and oxidative effects on living organisms.Selenium deficiency has been associated with impaired function of the immune system.Selenium deficiency appears to enhance the virulence or progression of some viral infections.Selenium deficiency results in decreased activity of glutathione peroxidase, increasing oxidative damage and the likelihood of mutations in the viral genome.The safe range of selenium intake is relatively small and excess selenium intake can readily result in toxicity.This review summarizes the updates of benefitial and adverse effects of selenium on health.