CAJ | 학술논문

越来越多研究表明,生酮饮食已开始用于癫痫以外的神经疾病的治疗.肿瘤细胞线粒体的缺损导致其不能利用酮体作为主要能量来源,生酮饮食能增加氧化应激作用,抑制信号通路传导,发挥抗肿瘤作用.此外,生酮饮食也能增加放化疗药物的抗肿瘤效应.生酮饮食在肿瘤模型和临床试验中表现出一定的治疗效果.
월래월다연구표명,생동음식이개시용우전간이외적신경질병적치료.종류세포선립체적결손도치기불능이용동체작위주요능량래원,생동음식능증가양화응격작용,억제신호통로전도,발휘항종류작용.차외,생동음식야능증가방화료약물적항종류효응.생동음식재종류모형화림상시험중표현출일정적치료효과.
Recently, more and more studies have indicated that the ketogenic diet began to be used for neurological conditions other than epilepsy.Because of mitochondrial defectiong, tumor cells are unable to use ketone bodies as a primary energy source.The ketogenic diet exerts anti-tumor effect by increasing oxidatetivesress and inhibiting the signal transduction.Besides, ketogenic diet may also enhance the anti-tumor effect of radiation therapy and chemotherapies.The ketogenic diets in tumor models and clinical trials have shown therapeutic effect.