CAJ | 학술논문

中性粒细胞呼吸爆发是把"双刃剑",一方面,中性粒细胞呼吸爆发在新生儿抵抗感染中扮演着重要的角色;另一方面,新生儿体内抗氧化物不足,容易受到中性粒细胞呼吸爆发所产生的活性氧物质损伤.已经有研究显示中性粒细胞呼吸爆发和新生儿新生儿疾病密切相关,如新生儿感染及支气管肺发育不良,但仍存在争议.该文从中性粒细胞呼吸爆发的炎症效应及检测方法、中性粒细胞呼吸爆发与新生儿感染以及中性粒细胞呼吸爆发与支气管肺发育不良三个部分对新生儿中性粒细胞呼吸爆发功能的研究进展进行综述.
중성립세포호흡폭발시파"쌍인검",일방면,중성립세포호흡폭발재신생인저항감염중분연착중요적각색;령일방면,신생인체내항양화물불족,용역수도중성립세포호흡폭발소산생적활성양물질손상.이경유연구현시중성립세포호흡폭발화신생인신생인질병밀절상관,여신생인감염급지기관폐발육불량,단잉존재쟁의.해문종중성립세포호흡폭발적염증효응급검측방법、중성립세포호흡폭발여신생인감염이급중성립세포호흡폭발여지기관폐발육불량삼개부분대신생인중성립세포호흡폭발공능적연구진전진행종술.
Neutrophil respiratory burst is like a double-edged sword.On one hand, newborns rely mainly on neutrophil against infection.On the other hand, newborns are succeptible to be damaged by reactive oxygen species.Studies have already suggested that reactive oxygen species have relationship with neonatal diseases, such as sepsis,bronchopulmonary dysplasia,but it still remains controversial.This paper provides an overview of the measurement of neutrophil respiratory burst, and the relationship of neutrophil respiratory burst with neonatal sepsis,as well as with bronchopulmonary dysplasia.