中国医药
中國醫藥
중국의약
China Medicine
2015年
12期
1808-1810
,共3页
膝关节骨性关节炎%骨龙胶囊%盐酸氨基葡萄糖片
膝關節骨性關節炎%骨龍膠囊%鹽痠氨基葡萄糖片
슬관절골성관절염%골룡효낭%염산안기포도당편
Knee osteoarthritis%Gulong capsule%Glucosamine hydrochloride tablets
目的 探讨骨龙胶囊联合盐酸氨基葡萄糖片治疗膝关节骨性关节炎(KOA)的临床效果.方法 选取2013年3月至2015年5月于北京军区总医院第三门诊部和骨科门诊就诊的膝关节骨性关节炎患者68例,完全随机分为观察组和对照组,各34例.观察组给予骨龙胶囊2.5g,3次/d口服,盐酸氨基葡萄糖片240 mg,3次/d口服;对照组给予盐酸氨基葡萄糖片240 mg,3次/d口服.分别观察治疗前及治疗后60d2组患者的关节疼痛程度、关节肿胀、关节活动度、步行能力的变化并评分,比较2组患者治疗效果.结果 治疗后,观察组总有效率88.2％ (30/34),其中临床治愈3例、显效16例、有效11例、无效4例;对照组总有效率64.7％ (22/34),其中临床治愈0例、显效9例、有效13例、无效12例,2组总有效率差异有统计学意义(P＜0.05).2组患者不良反应程度均较轻微,差异无统计学意义(P＞0.05).结论 应用骨龙胶囊联合盐酸氨基葡萄糖片治疗膝关节骨性关节炎安全有效,能够缓解关节疼痛,提高患者的生活质量.
目的 探討骨龍膠囊聯閤鹽痠氨基葡萄糖片治療膝關節骨性關節炎(KOA)的臨床效果.方法 選取2013年3月至2015年5月于北京軍區總醫院第三門診部和骨科門診就診的膝關節骨性關節炎患者68例,完全隨機分為觀察組和對照組,各34例.觀察組給予骨龍膠囊2.5g,3次/d口服,鹽痠氨基葡萄糖片240 mg,3次/d口服;對照組給予鹽痠氨基葡萄糖片240 mg,3次/d口服.分彆觀察治療前及治療後60d2組患者的關節疼痛程度、關節腫脹、關節活動度、步行能力的變化併評分,比較2組患者治療效果.結果 治療後,觀察組總有效率88.2％ (30/34),其中臨床治愈3例、顯效16例、有效11例、無效4例;對照組總有效率64.7％ (22/34),其中臨床治愈0例、顯效9例、有效13例、無效12例,2組總有效率差異有統計學意義(P＜0.05).2組患者不良反應程度均較輕微,差異無統計學意義(P＞0.05).結論 應用骨龍膠囊聯閤鹽痠氨基葡萄糖片治療膝關節骨性關節炎安全有效,能夠緩解關節疼痛,提高患者的生活質量.
목적 탐토골룡효낭연합염산안기포도당편치료슬관절골성관절염(KOA)적림상효과.방법 선취2013년3월지2015년5월우북경군구총의원제삼문진부화골과문진취진적슬관절골성관절염환자68례,완전수궤분위관찰조화대조조,각34례.관찰조급여골룡효낭2.5g,3차/d구복,염산안기포도당편240 mg,3차/d구복;대조조급여염산안기포도당편240 mg,3차/d구복.분별관찰치료전급치료후60d2조환자적관절동통정도、관절종창、관절활동도、보행능력적변화병평분,비교2조환자치료효과.결과 치료후,관찰조총유효솔88.2％ (30/34),기중림상치유3례、현효16례、유효11례、무효4례;대조조총유효솔64.7％ (22/34),기중림상치유0례、현효9례、유효13례、무효12례,2조총유효솔차이유통계학의의(P＜0.05).2조환자불량반응정도균교경미,차이무통계학의의(P＞0.05).결론 응용골룡효낭연합염산안기포도당편치료슬관절골성관절염안전유효,능구완해관절동통,제고환자적생활질량.
Objective To explore the effect of Gulong capsule combined with glucosamine hydrochloride tablet in treating knee osteoarthritis (KOA).Methords Totally 68 KOA patients from March 2012 to March 2015 were randomly divided into observation group (30 cases) orally given Gulong capsule (2.5 g, 3 times/d)combined with glucosamine hydrochloride tablet (240 mg, 3 tines/d), and control group (34 cases) orally given glucosamine hydrochloride tablet (240 mg, 3 times/d oral).Before and 60 days after treatment, the degree of arthralgia, arthroncus, range of motion and walking ability were assessed and graded;the effective rate and incidence of adverse reactions were compared between groups.Results In observation group, 3 cases were clinically cured, 16 cases were markedly effective, 11 cases were effective, 4 cases were ineffective;in control group, none was cured, 9 cases were markedly effective, 13 cases were effective, 12 cases were ineffective;the total effective rate in observation group was significantly higher than that in control group [88.2％ (30/34) vs 64.7％(22/34)] (P ＜ 0.05).The adverse reaction degree was relatively mild in both groups;the incidence of adverse reactions was not significantly different between groups (P ＞ 0.05).Conclusion Gulong capsule combined with glucosamine hydrochloride tablets is safe and effective in treating KOA, it can relieve joint pain and improve the life quality.
