CAJ | 학술논문

目的总结对老年恶性脑胶质瘤术后患者行常规放疗联合口服化疗药物替莫唑胺( TMZ)的护理体会. 方法收集2000年1月至2014年1月就诊于我科的23例患恶性胶质瘤老年患者,在采用放疗联合替莫唑胺化疗的同时,针对所有患者施行有效的护理. 结果 23 例同步放化疗患者中,出现恶心、呕吐者6 例,便秘者5例,乏力者1例,Ⅱ度骨髓抑制者1例,主要表现为白细胞计数下降,给予对症治疗后白细胞恢复正常,未延误放化疗的正常进行. 所有患者均未出现重度骨髓抑制及癫疒间发作,放疗后23例患者均出现局部脱发. 结论针对老年恶性脑胶质瘤术后患者,在同步放化疗的过程中,施行有效的个体化护理手段,可以明显降低老年患者的不良反应,对治疗有积极作用.
목적 총결대노년악성뇌효질류술후환자행상규방료연합구복화료약물체막서알( TMZ)적호리체회. 방법 수집2000년1월지2014년1월취진우아과적23례환악성효질류노년환자,재채용방료연합체막서알화료적동시,침대소유환자시행유효적호리. 결과 23 례동보방화료환자중,출현악심、구토자6 례,편비자5례,핍력자1례,Ⅱ도골수억제자1례,주요표현위백세포계수하강,급여대증치료후백세포회복정상,미연오방화료적정상진행. 소유환자균미출현중도골수억제급전녁간발작,방료후23례환자균출현국부탈발. 결론침대노년악성뇌효질류술후환자,재동보방화료적과정중,시행유효적개체화호리수단,가이명현강저노년환자적불량반응,대치료유적겁작용.
Objective To summarize the nursing experience of conventional radiotherapy combined with oral chemotherapy drug temozolomide ( TMZ ) in the treatment of elderly patients with malignant glioma after surgery. Methods Twenty three cases of elderly malignant glioma patients who were treated in our department from January 2000 to January 2014 were collected. The patients received radiotherapy combined temozolomide chemotherapy as well as effective nursing. Results During the treatment,there were 6 cases of nausea and vomiting, 5 cases of constipation, 1 case of weakness, and 1 case of Ⅱ myelosuppression which was reflected mainly by the decrease of white blood cells number. The white blood cells number returned to normal after the symptomatic treatment without delaying the normal radiation and chemotherapy. No severe bone marrow suppression or seizures was observed,but all the patients had local hair loss after radiotherapy. Conclusion The implementation of effective personal care measure can significantly re-duce the adverse reactions of elderly patients with malignant brain glioma after surgery and also play an active role in the process of synchronous radiotherapy and chemotherapy.