中华肝胆外科杂志
中華肝膽外科雜誌
중화간담외과잡지
Chinese Journal of Hepatobiliary Surgery
2015年
11期
761-764
,共4页
胰腺癌%糖尿病%术后血糖%预后
胰腺癌%糖尿病%術後血糖%預後
이선암%당뇨병%술후혈당%예후
Pancreatic carcinoma%Diabetes mellitus%Postoperative blood glucose%Prognosis
目的 探讨糖尿病及术后血糖控制情况对接受根治手术的胰腺癌患者的临床病理特征和预后的影响.方法 回顾性分析天津医科大学总医院2010年1月至2015年1月83例接受胰腺癌根治手术治疗的胰腺癌患者的临床与随访资料.根据术前是否合并糖尿病将患者分为糖尿病组(28例)和非糖尿病组(55例).比较两组患者临床病理特征、术后情况、预后以及术后血糖对预后的影响.结果 糖尿病组与非糖尿病组患者术后血糖控制不良的发生率分别为71.4%(20/28)和20.0%(11/55),差异有统计学意义(P<0.05).糖尿病组与非糖尿病组患者术后3年生存率分别为11.3%和31.8%,差异有统计学意义(P<0.05);术后血糖控制不良与术后血糖控制良好的胰腺癌患者术后3年生存率分别为8.8%和34.6%,差异有统计学意义(P<0.05).结论 胰腺癌合并糖尿病的患者根治手术后血糖较难控制,且预后较差;根治术后血糖控制不良的胰腺癌患者预后较差.
目的 探討糖尿病及術後血糖控製情況對接受根治手術的胰腺癌患者的臨床病理特徵和預後的影響.方法 迴顧性分析天津醫科大學總醫院2010年1月至2015年1月83例接受胰腺癌根治手術治療的胰腺癌患者的臨床與隨訪資料.根據術前是否閤併糖尿病將患者分為糖尿病組(28例)和非糖尿病組(55例).比較兩組患者臨床病理特徵、術後情況、預後以及術後血糖對預後的影響.結果 糖尿病組與非糖尿病組患者術後血糖控製不良的髮生率分彆為71.4%(20/28)和20.0%(11/55),差異有統計學意義(P<0.05).糖尿病組與非糖尿病組患者術後3年生存率分彆為11.3%和31.8%,差異有統計學意義(P<0.05);術後血糖控製不良與術後血糖控製良好的胰腺癌患者術後3年生存率分彆為8.8%和34.6%,差異有統計學意義(P<0.05).結論 胰腺癌閤併糖尿病的患者根治手術後血糖較難控製,且預後較差;根治術後血糖控製不良的胰腺癌患者預後較差.
목적 탐토당뇨병급술후혈당공제정황대접수근치수술적이선암환자적림상병리특정화예후적영향.방법 회고성분석천진의과대학총의원2010년1월지2015년1월83례접수이선암근치수술치료적이선암환자적림상여수방자료.근거술전시부합병당뇨병장환자분위당뇨병조(28례)화비당뇨병조(55례).비교량조환자림상병리특정、술후정황、예후이급술후혈당대예후적영향.결과 당뇨병조여비당뇨병조환자술후혈당공제불량적발생솔분별위71.4%(20/28)화20.0%(11/55),차이유통계학의의(P<0.05).당뇨병조여비당뇨병조환자술후3년생존솔분별위11.3%화31.8%,차이유통계학의의(P<0.05);술후혈당공제불량여술후혈당공제량호적이선암환자술후3년생존솔분별위8.8%화34.6%,차이유통계학의의(P<0.05).결론 이선암합병당뇨병적환자근치수술후혈당교난공제,차예후교차;근치술후혈당공제불량적이선암환자예후교차.
Objective To study the impact of diabetes mellitus (DM) and postoperative blood glucose control on the clinicopathological characteristics and prognosis of patients with pancreatic cancer who underwent radical surgery.Methods From January 2010 to January 2015, the clinical and follow-up data of 83 patients with pancreatic cancer who underwent radical surgery at Tianjin Medical University General Hospital were retrospectively studied.Patients were classified into the diabetic group (28 cases) and the non-diabetic group (55 cases) according to the preoperative status of DM.The clinicopathological characteristics, postoperative conditions and prognosis were compared.Results The incidences in the two groups of patients whose postoperative blood glucose levels were poorly controlled were 71.4% (20/28) and 20.0% (11/55) in the diabetes group and the non-diabetic groups, respectively.The difference was significant (P <0.05).The 3-year survival rate of the diabetic and the non-diabetic groups were 11.3% and 31.8% , respectively.The difference was significant (P < 0.05).The 3-year survival rate of patients with poorly-controlled blood glucose levels were 8.8%, and 34.6%, respectively.The difference was significant (P < 0.05).Conclusions The postoperative blood glucose level in pancreatic cancer patients with DM was poorly controlled after radical surgery.The prognosis of pancreatic cancer patients with DM or poorly postoperative blood glucose control was poor after radical surgery.