中华胃肠外科杂志
中華胃腸外科雜誌
중화위장외과잡지
Chinese Journal of Gastrointestinal Surgery
2015年
11期
1128-1131
,共4页
胃肿瘤%腹腔冲洗%脱落细胞%淋巴结转移
胃腫瘤%腹腔遲洗%脫落細胞%淋巴結轉移
위종류%복강충세%탈락세포%림파결전이
Stomach neoplasms%Peritoneal lavage%Exfoliated carcinoma cells%Lymph nodes metastasis
目的 探讨影响胃癌患者腹腔冲洗脱落细胞阳性的临床病理因素.方法 回顾性分析2013年6月至2014年5月间在哈尔滨医科大学附属肿瘤医院胃肠外科接受胃癌根治术治疗并进行腹腔冲洗(1000 ml生理盐水)脱落细胞学检查的163例胃癌患者的临床病理资料.并对切除病灶及术中清扫的淋巴结分组装袋做病理学检查及免疫组织化学检测.对可能影响胃癌患者腹腔冲洗脱落细胞的因素进行单因素和多因素Logistic回归分析.结果 163例胃癌患者腹腔冲洗脱落细胞阳性15例(9.2％).单因素分析显示,患者病理分期、肿瘤浸润深度、N分期、淋巴结转移站别、有无淋巴结转移、淋巴结转移率、第2站淋巴结转移率以及组织分化程度与腹腔冲洗脱落细胞阳性有关(均P＜0.05).多因素分析显示,第2站淋巴结转移率是影响胃癌患者腹腔冲洗脱落细胞阳性的独立危险因素(OR=6.366,95％ CI: 1.650～24.555,P=0.007).结论 影响胃癌患者腹腔冲洗脱落细胞阳性的独立危险因素是第2站淋巴结转移率.
目的 探討影響胃癌患者腹腔遲洗脫落細胞暘性的臨床病理因素.方法 迴顧性分析2013年6月至2014年5月間在哈爾濱醫科大學附屬腫瘤醫院胃腸外科接受胃癌根治術治療併進行腹腔遲洗(1000 ml生理鹽水)脫落細胞學檢查的163例胃癌患者的臨床病理資料.併對切除病竈及術中清掃的淋巴結分組裝袋做病理學檢查及免疫組織化學檢測.對可能影響胃癌患者腹腔遲洗脫落細胞的因素進行單因素和多因素Logistic迴歸分析.結果 163例胃癌患者腹腔遲洗脫落細胞暘性15例(9.2％).單因素分析顯示,患者病理分期、腫瘤浸潤深度、N分期、淋巴結轉移站彆、有無淋巴結轉移、淋巴結轉移率、第2站淋巴結轉移率以及組織分化程度與腹腔遲洗脫落細胞暘性有關(均P＜0.05).多因素分析顯示,第2站淋巴結轉移率是影響胃癌患者腹腔遲洗脫落細胞暘性的獨立危險因素(OR=6.366,95％ CI: 1.650～24.555,P=0.007).結論 影響胃癌患者腹腔遲洗脫落細胞暘性的獨立危險因素是第2站淋巴結轉移率.
목적 탐토영향위암환자복강충세탈락세포양성적림상병리인소.방법 회고성분석2013년6월지2014년5월간재합이빈의과대학부속종류의원위장외과접수위암근치술치료병진행복강충세(1000 ml생리염수)탈락세포학검사적163례위암환자적림상병리자료.병대절제병조급술중청소적림파결분조장대주병이학검사급면역조직화학검측.대가능영향위암환자복강충세탈락세포적인소진행단인소화다인소Logistic회귀분석.결과 163례위암환자복강충세탈락세포양성15례(9.2％).단인소분석현시,환자병리분기、종류침윤심도、N분기、림파결전이참별、유무림파결전이、림파결전이솔、제2참림파결전이솔이급조직분화정도여복강충세탈락세포양성유관(균P＜0.05).다인소분석현시,제2참림파결전이솔시영향위암환자복강충세탈락세포양성적독립위험인소(OR=6.366,95％ CI: 1.650～24.555,P=0.007).결론 영향위암환자복강충세탈락세포양성적독립위험인소시제2참림파결전이솔.
Objective To explore the clinicopathological factors affecting positive cells in peritoneal lavage of gastric carcinoma.Methods Clinicopathological data of 163 patients undergoing radical operation for gastric carcinoma and receiving cytology examination of peritoneal lavage (1000 ml normal saline) in our department from June 2013 to May 2014 were analyzed retrospectively.Pathology and immunohistochemistry were performed for resected lesions and harvested lymph nodes.Affecting factors of peritoneal lavage cytology were evaluated with univariate and multivariate logistic analyses.Results The positive rate of exfoliative carcinoma cells was 9.2％(15/163).Univariate analysis showed that pathologic staging, depth of invasion, N staging, lymph node metastasis, station of positive lymph node, metastatic rate of lymph node, metastatic rate of the second station of lymph node, and carcinoma differentiation degree were associated with the positive rate of peritoneal lavage cytology (all P＜0.05).Multivariate analysis revealed only the metastatic rate of the second station of lymph node was independent risk factor of positive exfoliative cells in peritoneal lavage.Conclusion The metastatic rate of the second station of lymph node is an independent risk factor of positive exfoliative cells in peritoneal lavage for gastric cancer patients.
