CAJ | 학술논문

目的:探究中医体质学说中气郁质与平和质的磁共振血氧依赖性脑功能成像特点及意义.方法:选取 2011 年 5月—2013年5月20例行头部功能磁共振成像(FMRI)检验的受检者,其中包括平和质12例,气郁质8例,对所有受检者进行全脑解剖像扫描、选定区域功能像扫描,采用情绪图片刺激试验来观察两种体质受检者的FMRI图像变化情况.结果:同组内同一条件下左、右杏仁核激活体积对比有差异,左侧激活体积较右侧大;同组内同侧杏仁核在不同条件下的比较,平和质组在喜悦图片下的激活体积较悲伤图片大,而气郁质组对比无统计学意义;两组间同一条件下左、右杏仁核分别比较,气郁质的双侧杏仁核激活体积均较平和质减低,以喜悦图片下减低明显.结论:FMRI可以对不同中医体质人群的脑功能成像进行定位和定量分析,气郁质、平和质人群脑部均存在一定的激活区,在杏仁核区域的分布较为集中,且气郁质人群的杏仁核在脑功能成像中的激活体积较平和质减低,喜悦图片下激活体积更小.
목적:탐구중의체질학설중기욱질여평화질적자공진혈양의뢰성뇌공능성상특점급의의.방법:선취 2011 년 5월—2013년5월20례행두부공능자공진성상(FMRI)검험적수검자,기중포괄평화질12례,기욱질8례,대소유수검자진행전뇌해부상소묘、선정구역공능상소묘,채용정서도편자격시험래관찰량충체질수검자적FMRI도상변화정황.결과:동조내동일조건하좌、우행인핵격활체적대비유차이,좌측격활체적교우측대;동조내동측행인핵재불동조건하적비교,평화질조재희열도편하적격활체적교비상도편대,이기욱질조대비무통계학의의;량조간동일조건하좌、우행인핵분별비교,기욱질적쌍측행인핵격활체적균교평화질감저,이희열도편하감저명현.결론:FMRI가이대불동중의체질인군적뇌공능성상진행정위화정량분석,기욱질、평화질인군뇌부균존재일정적격활구,재행인핵구역적분포교위집중,차기욱질인군적행인핵재뇌공능성상중적격활체적교평화질감저,희열도편하격활체적경소.
Objective: To explore the characteristics and significance of BOLD-fMRI Functional Brain Imaging of Qi-stagnation constitution and constitution of yin-yang harmony. Methods: 20 patients, 12 Qi-stagnation constitution patients and 8 patients ofconstitution of yin-yang harmony, were given head functional magnetic resonance imaging (FMRI) in addition to whole brain anatomy image scanning, selected area function image scanning. Results: left and right amygdala activation volume was significantly different in the same group, the outcome of patients of constitution of yin-yang harmony excelled that of i-stagnation constitution patients. Conclusion:FMRI can carry out the localization and quantitative analysis of cerebral functional imaging in different TCM Constitutions.