CAJ | 학술논문

目的系统评价半夏泻心汤合并西药对胆汁反流性胃炎的临床疗效.方法计算机检索文献,并按标准筛选,进行质量评价,纳入12篇随机对照试验研究文献,采用Cochrane协作网的RevManv5.3软件,以总有效率、嗳气缓解及胃脘痛缓解3个指标进行Meta分析.结果在嗳气缓解方面,半夏泻心汤合并西药治疗试验组与对照组之间差异无统计学意义( P>0.05 );而在总有效率及胃脘痛缓解方面,试验组与对照组之间差异有统计学意义 ( P <0.05 ).结论半夏泻心汤合并西药治疗胆汁反流性胃炎有较好疗效,且能有效缓解患者胃脘痛,但在对改善患者嗳气上并无显著优势.
목적 계통평개반하사심탕합병서약대담즙반류성위염적림상료효.방법 계산궤검색문헌,병안표준사선,진행질량평개,납입12편수궤대조시험연구문헌,채용Cochrane협작망적RevManv5.3연건,이총유효솔、애기완해급위완통완해3개지표진행Meta분석.결과 재애기완해방면,반하사심탕합병서약치료시험조여대조조지간차이무통계학의의( P>0.05 );이재총유효솔급위완통완해방면,시험조여대조조지간차이유통계학의의 ( P <0.05 ).결론 반하사심탕합병서약치료담즙반류성위염유교호료효,차능유효완해환자위완통,단재대개선환자애기상병무현저우세.
Objective To evaluate whether Banxiaxiexin decoction com-bined with western medicine treatment has remarkable clinical effect on the patients with bile reflux gastritis ( BRG) .Methods Correlative literatures were searched by computer. A total of twelve studies of randomized controlled trial were brought into this research according to the inclusion and the exclusion criteria.Meta-analysis was used in three aspects including total effective rate, belching relief and epigastric pain relief.Results It showed significant differences in total effective rate and epigastric pain relief,but no significant difference in belching relief. Conclusion Banxiaxiexin decoction for purging stomach-fire combined with western medicine treatment was beneficial to improve the total effective rate and relieve epigastric pain of patients with bile reflux gastri-tis, but had no significant advantage to improve the belching.