中国临床药理学杂志
中國臨床藥理學雜誌
중국림상약이학잡지
The Chinese Journal of Clinical Pharmacology
2015年
22期
2187-2189
,共3页
前列舒通%左氧氟沙星%前列腺炎%临床疗效%安全性
前列舒通%左氧氟沙星%前列腺炎%臨床療效%安全性
전렬서통%좌양불사성%전렬선염%림상료효%안전성
Qianlieshutong%levofloxacin%prostatitis%clinical efficacy%safety
目的 评价前列舒通联合左氧氟沙星治疗慢性细菌性前列腺炎的临床疗效和安全性. 方法 将135例慢性细菌性前列腺炎患者随机分为试验组71例和对照组64例. 试验组予以口服前列舒通,每次0.4 g,每日3次+左氧氟沙星,每次0.1 g,每日2次;对照组予以左氧氟沙星,每次0.1 g,每日2次. 2组患者疗程均为2周. 比较2组患者的临床疗效、细菌学疗效和不良反应发生率.结果 试验组的有效率为60.56%显著优于对照组51.56%( P<0.05). 试验组的细菌清除率为100.00%显著优于对照组72.22%( P<0.05 ). 试验组和对照组的不良反应发生率分别为4.23%和3.13%,差异无统计学意义( P>0.05 ).结论 前列舒通联合左氧氟沙星治疗前列腺炎的临床疗效确切,且不增加不良反应的发生率.
目的 評價前列舒通聯閤左氧氟沙星治療慢性細菌性前列腺炎的臨床療效和安全性. 方法 將135例慢性細菌性前列腺炎患者隨機分為試驗組71例和對照組64例. 試驗組予以口服前列舒通,每次0.4 g,每日3次+左氧氟沙星,每次0.1 g,每日2次;對照組予以左氧氟沙星,每次0.1 g,每日2次. 2組患者療程均為2週. 比較2組患者的臨床療效、細菌學療效和不良反應髮生率.結果 試驗組的有效率為60.56%顯著優于對照組51.56%( P<0.05). 試驗組的細菌清除率為100.00%顯著優于對照組72.22%( P<0.05 ). 試驗組和對照組的不良反應髮生率分彆為4.23%和3.13%,差異無統計學意義( P>0.05 ).結論 前列舒通聯閤左氧氟沙星治療前列腺炎的臨床療效確切,且不增加不良反應的髮生率.
목적 평개전렬서통연합좌양불사성치료만성세균성전렬선염적림상료효화안전성. 방법 장135례만성세균성전렬선염환자수궤분위시험조71례화대조조64례. 시험조여이구복전렬서통,매차0.4 g,매일3차+좌양불사성,매차0.1 g,매일2차;대조조여이좌양불사성,매차0.1 g,매일2차. 2조환자료정균위2주. 비교2조환자적림상료효、세균학료효화불량반응발생솔.결과 시험조적유효솔위60.56%현저우우대조조51.56%( P<0.05). 시험조적세균청제솔위100.00%현저우우대조조72.22%( P<0.05 ). 시험조화대조조적불량반응발생솔분별위4.23%화3.13%,차이무통계학의의( P>0.05 ).결론 전렬서통연합좌양불사성치료전렬선염적림상료효학절,차불증가불량반응적발생솔.
Objective To evaluate the clinical efficacy and safety of the combination of Qianlieshutong and levofloxacin in the treatment of pa-tients with chronic bacterial prostatitis.Methods One hundred thirty-five patients with chronic bacterial prostatitis were randomly divided into treatment group (n=71) and control group (n=64).Patients in treat-ment group were treated with qianlieshutong 0.4 g, po, 3 times a day and levofloxacin 0.1 g, twice a day.Patients in control group were trea-ted with levofloxacin 0.1 g, twice a day.The course of treatment was 2 weeks in two groups.The clinical efficacy, bacteriological efficacy and incidence of adverse drug reactions between the two groups were com-pared.Results The effective rate of treatment group ( 60.56%) was significantly higher than that of control group (51.56%, P<0.05).The bacterial clear rate of treatment group ( 100.00%) was significantly higher than that of control group ( 72.22%, P<0.05 ) .The incidences of adverse reactions were 4.23%and 3.13%in the treatment group and control group respectively without statistical difference ( P >0.05 ) . Conclusion The clinical efficacy of Qianlieshutong combine with levofloxacin in the treatment of prostatitis is exact, and without increasing incidence of adverse drug reactions.
