CAJ | 학술논문

目的评价早期高容量血液滤过对心肺复苏后综合征患者预后的影响.方法 44例心肺复苏后综合征患者,随机分为试验组和对照组,各22例. 试验组于入院6h内实施早期高容量血液滤过治疗,对照组在入院6h后实施高容量血液滤过治疗,观察2 组患者治疗前、治疗6d 后急性生理与慢性健康评分(APACHEⅡ)、多器官功能障碍综合征(MODS)评分、血清C反应蛋白(CRP)、血清降钙素原( PCT)水平变化以及多巴胺用量、平均动脉压、氧合指数变化情况.结果 2组患者治疗后APACHEⅡ评分、MODS评分以及血清CRP、PCT水平与治疗前相比均得到改善、多巴胺用量显著降低( P<0.05 ) ,其中试验组治疗后APACHEⅡ评分、MODS评分、多巴胺用量、血清CRP、PCT水平明显低于对照组( P <0.05 ) ,而平均动脉压与氧合指数均显著高于对照组( P <0.05 ).结论早期高容量血液滤过对心肺复苏后综合征患者预后有积极意义.
목적 평개조기고용량혈액려과대심폐복소후종합정환자예후적영향.방법 44례심폐복소후종합정환자,수궤분위시험조화대조조,각22례. 시험조우입원6h내실시조기고용량혈액려과치료,대조조재입원6h후실시고용량혈액려과치료,관찰2 조환자치료전、치료6d 후급성생리여만성건강평분(APACHEⅡ)、다기관공능장애종합정(MODS)평분、혈청C반응단백(CRP)、혈청강개소원( PCT)수평변화이급다파알용량、평균동맥압、양합지수변화정황.결과 2조환자치료후APACHEⅡ평분、MODS평분이급혈청CRP、PCT수평여치료전상비균득도개선、다파알용량현저강저( P<0.05 ) ,기중시험조치료후APACHEⅡ평분、MODS평분、다파알용량、혈청CRP、PCT수평명현저우대조조( P <0.05 ) ,이평균동맥압여양합지수균현저고우대조조( P <0.05 ).결론 조기고용량혈액려과대심폐복소후종합정환자예후유적겁의의.
Objective To evaluate the effect of early high -volume hemofiltration in the treatment and prognosis of post -resuscitation syndrome( PRS).Methods A total of 44 patients wiht PRS were ran-domly divided into the trial group and the control group, and all patients were treated by conventional treatment.The patients in the trial group were treated by early high-volume hemofiltration within 6 h, while the patients in the control group were treated by high-volume hemofiltration after 6 h.Acute physiology and chronic health evaluation ( APACHEII) , multiple organ dysfunction syndrome evaluation ( MODS ) , C -reactive protein(CRP), procalcitonin(PCT), dopamine dosage, mean arterial pressure(MAP), and oxygenation index were recorded.Results The APACHE Ⅱ score, MODS score, serum CRP and PCT level improved and dopamine dosage decreased after treatment in two groups compared with those before treatment (P<0.05), but the parameters in trial group were significantly lower than those in control group ( P<0.05) , and MAP and oxygenation index in the trial group were significantly higher than those in the control group ( P <0.05 ) . Conclusion Early high-volume hemofiltration is effective in the treatment and prognosis of PRS with positive significance.