中国现代医药杂志
中國現代醫藥雜誌
중국현대의약잡지
Modern Medicine Journal of China
2015年
10期
52-54
,共3页
肝性脑病%乳果糖%保留灌肠
肝性腦病%乳果糖%保留灌腸
간성뇌병%유과당%보류관장
Hepatic encephalopathy%Lactulose%Vetention enema
目的 比较家庭乳果糖保留灌肠及口服治疗对预防再发肝性脑病的疗效.方法 选择2013年1月~2014年12月确诊的肝硬化肝性脑病经治疗后出院患者70例,随机分为两组(口服组和灌肠组). 除基础治疗外,口服组加用乳果糖口服,灌肠组在家加用乳果糖保留灌肠.比较两组患者出院当天及出院1个月后返院复查时精神状态、血氨、数字连接试验及再次住院情况. 结果 ①灌肠组精神状态改变量平均秩次为26.62,口服组精神状态改变量平均秩次为37.69,灌肠组的良好精神状态维持情况优于口服组(P=0.001);②口服组血氨水平改变量平均秩次为37.25,灌肠组血氨水平改变量平均秩次为27.12,灌肠组血氨下降程度明显大于口服组(P=0.03);③两组数字连接试验所需时间改变程度及再入院情况差异无统计学意义.结论 出院后进行家庭乳果糖灌肠,对于维持肝硬化肝性脑病患者的精神状态、改善血氨水平,效果优于乳果糖口服治疗.
目的 比較傢庭乳果糖保留灌腸及口服治療對預防再髮肝性腦病的療效.方法 選擇2013年1月~2014年12月確診的肝硬化肝性腦病經治療後齣院患者70例,隨機分為兩組(口服組和灌腸組). 除基礎治療外,口服組加用乳果糖口服,灌腸組在傢加用乳果糖保留灌腸.比較兩組患者齣院噹天及齣院1箇月後返院複查時精神狀態、血氨、數字連接試驗及再次住院情況. 結果 ①灌腸組精神狀態改變量平均秩次為26.62,口服組精神狀態改變量平均秩次為37.69,灌腸組的良好精神狀態維持情況優于口服組(P=0.001);②口服組血氨水平改變量平均秩次為37.25,灌腸組血氨水平改變量平均秩次為27.12,灌腸組血氨下降程度明顯大于口服組(P=0.03);③兩組數字連接試驗所需時間改變程度及再入院情況差異無統計學意義.結論 齣院後進行傢庭乳果糖灌腸,對于維持肝硬化肝性腦病患者的精神狀態、改善血氨水平,效果優于乳果糖口服治療.
목적 비교가정유과당보류관장급구복치료대예방재발간성뇌병적료효.방법 선택2013년1월~2014년12월학진적간경화간성뇌병경치료후출원환자70례,수궤분위량조(구복조화관장조). 제기출치료외,구복조가용유과당구복,관장조재가가용유과당보류관장.비교량조환자출원당천급출원1개월후반원복사시정신상태、혈안、수자련접시험급재차주원정황. 결과 ①관장조정신상태개변량평균질차위26.62,구복조정신상태개변량평균질차위37.69,관장조적량호정신상태유지정황우우구복조(P=0.001);②구복조혈안수평개변량평균질차위37.25,관장조혈안수평개변량평균질차위27.12,관장조혈안하강정도명현대우구복조(P=0.03);③량조수자련접시험소수시간개변정도급재입원정황차이무통계학의의.결론 출원후진행가정유과당관장,대우유지간경화간성뇌병환자적정신상태、개선혈안수평,효과우우유과당구복치료.
Objective To compare the preventive effect of lactulose on recurrent hepatic encephalopathy (HE) by vetention enema and oral in home cures. Methods 70 HE patients discharged from hospital after recovery in our hospital from Jan 2013 to Dec 2014 were randomly devided into two groups , the oral group and ventention enema group. Both groups were given the basic treatment after out-hospital, besides that, the oral group were given the lactulose by oral while the other group were given the lactulose by ventention enema. The treatment was lasted for one month and the mental state, blood ammonia, number connection test (NCT) and the state of rehospitalization were compared. Results The maintenance of mental state and the improvement degree of blood ammonia of ventention enema group were significantly better than those of the oral group (P=0.001, P=0.03). There were no significant differences in time change of NCT and rehospitalization between the two groups. Conclusion It is better for HE patients to take lactulose by vetention enema in home cures to maintain the mental state and improve blood ammonia than by oral.
