中国现代医药杂志
中國現代醫藥雜誌
중국현대의약잡지
Modern Medicine Journal of China
2015年
10期
45-47
,共3页
胫腓骨骨折%地佐辛%帕瑞昔布钠%超前镇痛
脛腓骨骨摺%地佐辛%帕瑞昔佈鈉%超前鎮痛
경비골골절%지좌신%파서석포납%초전진통
Fracture of tibia and fibula%Dezocine%Parecoxib sodium%Preemptive analgesia
目的 分析帕瑞昔布钠复合地佐辛治疗胫腓骨骨折切开复位内固定手术患者超前镇痛的效果. 方法 2013年8月~2015年4月于我院就诊的140例胫腓骨骨折患者,根据随机数字表法分为观察组和对照组,每组70例. 两组患者经术前全身麻醉后,在切皮前对照组静脉注射帕瑞昔布钠40mg,观察组静脉注射帕瑞昔布钠40mg和地佐辛0.1mg/kg. 对比两组患者胫腓骨骨折切开复位内固定术后的意识恢复时间和拔管后镇静躁动评分(SAS). 两组患者均在术后6个月进行随访,比较两组患者膝关节功能恢复情况HSS评分以及回访优良率.结果 观察组患者经过帕瑞昔布钠复合地佐辛治疗后的意识恢复时间为(10.18±3.06)min、镇静躁动SAS评分为(4.00±0.50)分、膝关节功能HSS评分为(79.17±8.24)分以及回访优良率94.29%,明显优于对照组意识恢复时间(11.69±3.34)min、镇静躁动SAS评分(4.30±0.80)分、膝关节功能HSS评分(75.79±7.09)分以及回访优良率75.71%,差异具有统计学意义(P<0.05). 结论 应用帕瑞昔布钠复合地佐辛在胫腓骨骨折切开复位内固定术中患者超前镇痛作用较为显著,患者术后意识恢复期短、愈合快、膝关节功能恢复较好以及回访优良率高.
目的 分析帕瑞昔佈鈉複閤地佐辛治療脛腓骨骨摺切開複位內固定手術患者超前鎮痛的效果. 方法 2013年8月~2015年4月于我院就診的140例脛腓骨骨摺患者,根據隨機數字錶法分為觀察組和對照組,每組70例. 兩組患者經術前全身痳醉後,在切皮前對照組靜脈註射帕瑞昔佈鈉40mg,觀察組靜脈註射帕瑞昔佈鈉40mg和地佐辛0.1mg/kg. 對比兩組患者脛腓骨骨摺切開複位內固定術後的意識恢複時間和拔管後鎮靜躁動評分(SAS). 兩組患者均在術後6箇月進行隨訪,比較兩組患者膝關節功能恢複情況HSS評分以及迴訪優良率.結果 觀察組患者經過帕瑞昔佈鈉複閤地佐辛治療後的意識恢複時間為(10.18±3.06)min、鎮靜躁動SAS評分為(4.00±0.50)分、膝關節功能HSS評分為(79.17±8.24)分以及迴訪優良率94.29%,明顯優于對照組意識恢複時間(11.69±3.34)min、鎮靜躁動SAS評分(4.30±0.80)分、膝關節功能HSS評分(75.79±7.09)分以及迴訪優良率75.71%,差異具有統計學意義(P<0.05). 結論 應用帕瑞昔佈鈉複閤地佐辛在脛腓骨骨摺切開複位內固定術中患者超前鎮痛作用較為顯著,患者術後意識恢複期短、愈閤快、膝關節功能恢複較好以及迴訪優良率高.
목적 분석파서석포납복합지좌신치료경비골골절절개복위내고정수술환자초전진통적효과. 방법 2013년8월~2015년4월우아원취진적140례경비골골절환자,근거수궤수자표법분위관찰조화대조조,매조70례. 량조환자경술전전신마취후,재절피전대조조정맥주사파서석포납40mg,관찰조정맥주사파서석포납40mg화지좌신0.1mg/kg. 대비량조환자경비골골절절개복위내고정술후적의식회복시간화발관후진정조동평분(SAS). 량조환자균재술후6개월진행수방,비교량조환자슬관절공능회복정황HSS평분이급회방우량솔.결과 관찰조환자경과파서석포납복합지좌신치료후적의식회복시간위(10.18±3.06)min、진정조동SAS평분위(4.00±0.50)분、슬관절공능HSS평분위(79.17±8.24)분이급회방우량솔94.29%,명현우우대조조의식회복시간(11.69±3.34)min、진정조동SAS평분(4.30±0.80)분、슬관절공능HSS평분(75.79±7.09)분이급회방우량솔75.71%,차이구유통계학의의(P<0.05). 결론 응용파서석포납복합지좌신재경비골골절절개복위내고정술중환자초전진통작용교위현저,환자술후의식회복기단、유합쾌、슬관절공능회복교호이급회방우량솔고.
Objective To analyze the preemptive analgesic effect of parecoxib sodium combined with dezocine on pa-tients with tibial and fibula fractures with open reduction and internal fixation. Methods From Aug 2013 to Apr 2015, 140 cases of patients with fracture of tibia and fibula fractures treated in our hospital were randomly divided into observation group and control group, 70 cases in each group. The patients of control group were treated with intravenous injection of parecoxib sodium 40mg, and the patients of observation group were given parecoxib sodium 40mg and dezocine 0.1mg/kg after preoperative general anesthesia and before skin incision. The consciousness recovery time, SAS score after extubation and HSS score, the excellent rate after 6 months of follow-up were compared between the two groups. Results The consciousness recovery time, SAS score, HSS score and the excellent rate of obsevation group were better than those of control group, and the differences had statistical signifficance (P<0.05). Conclusion Preemptive analgesia effect of parecoxib sodium combined with dezocine on patients with tibia and fibula frature with open reduction and internal fixation operation is obvious , it has short consciousness re-covery time, quick healing, good knee function recovery and high excellent rate.
