CAJ | 학술논문

通过75例女性良、恶性乳腺肿瘤及正常乳腺组织的傅里叶变换红外光谱（FTIR）对比研究发现，它们之间存在着明显而规律的光谱差异，这反映了组织中蛋白质，核酸和脂类等生物分子在不同性质的乳腺肿瘤中的构型与构像以及相对含量上的差别。研究表明，FTIR可从分子水平上揭示肿瘤组织的特性，能对良、恶性乳腺肿瘤的鉴别提供丰富而可靠的结构信息，极有可能发展成为一种肿瘤鉴别方法。
통과75례녀성량、악성유선종류급정상유선조직적부리협변환홍외광보（FTIR）대비연구발현，타문지간존재착명현이규률적광보차이，저반영료조직중단백질，핵산화지류등생물분자재불동성질적유선종류중적구형여구상이급상대함량상적차별。연구표명，FTIR가종분자수평상게시종류조직적특성，능대량、악성유선종류적감별제공봉부이가고적결구신식，겁유가능발전성위일충종류감별방법。
Infrared spectra of breast tissues from 75 female patients havebeen measured, and some remarkable spectral differences were observed among the benign, malignant and normal tissue samples. The frequency, shape and intensity of the bands indicated significant differences of content, structure and conformation of proteins, nucleic acids and lipids in different types of breast tumors. The present results suggested that Fourier transform infraned spectrometry (FTIR) could show the properties of tumors at the molecular level. It was able to supply rich and reliable information to investigation of benign and malignant tumors of human breast and be used as a convenient and reliable diagnostic tool for some tumors.