CAJ | 학술논문

目的:研究药用植物南欧大戟中的化学成分.方法:采用多种色谱手段和重结晶等方法,分离纯化化合物:根据化合物的理化性质和波谱数据鉴定其结构.结果:从南欧大戟全草的95%乙醇提取物的石油醚萃取部位分离得到4个单体化合物,包括3个二萜和1个甾醇.分别鉴定为:2,5,9,14-tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(1),3,5,7,15-pentaacetoxy-9-nicotinoyloxy-14-oxojatropha-6(17),11E-diene(2),2,5,7,8,14-hexaacetoxy-3-benzoyloxy9-nicotinoyloxy-15-hydroxy-jatropha-6(17),11E-diene(3)和β-谷甾醇(4).结论:上述4个化舍物均为首次从我国南欧大戟植物中分离得到.
목적:연구약용식물남구대극중적화학성분.방법:채용다충색보수단화중결정등방법,분리순화화합물:근거화합물적이화성질화파보수거감정기결구.결과:종남구대극전초적95%을순제취물적석유미췌취부위분리득도4개단체화합물,포괄3개이첩화1개치순.분별감정위:2,5,9,14-tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(1),3,5,7,15-pentaacetoxy-9-nicotinoyloxy-14-oxojatropha-6(17),11E-diene(2),2,5,7,8,14-hexaacetoxy-3-benzoyloxy9-nicotinoyloxy-15-hydroxy-jatropha-6(17),11E-diene(3)화β-곡치순(4).결론:상술4개화사물균위수차종아국남구대극식물중분리득도.
Objective:To study the ehemieal constituents of Euphorbia peplus Linn.Methods:All compounds were isolated and purified by many methods,including siliga gel and reversed phase RP-18 column ehmmatographies,MCI column,Sephadex LH-20,and recrystallization.Their structures were mainly elucidated by EI-MS,NMR including 2DNMR spectra and their physical characters.Results:Seven compounds(1-4)were isolated from the petroleum ether extract of 95%ethanol of the material.Their structures were identified as 2,5,9,14-tetrtmcetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(1),3,5,7,15-tetraaeetoxy-9-nicotinoyloxy-14-oxojatropha-6(17),11E-diene(2),2,5,7,8,14-pentaacetoxy-3-bemoyloxy-9-nicotinoyloxy-15-hydroxyjatropha-6(17),11E-diene(3),and β-sitosterol(4).Conclusion:All the compounds(1-4)were isolated from Euphorbia peplus Linn.Which collected in China for the first time.