中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2014年
7期
177-178
,共2页
韩亚男%张锦伟%许琳靖
韓亞男%張錦偉%許琳靖
한아남%장금위%허림정
HCV%RNA%实时荧光定量PCR%丙型肝炎病毒抗体
HCV%RNA%實時熒光定量PCR%丙型肝炎病毒抗體
HCV%RNA%실시형광정량PCR%병형간염병독항체
Hepatitis C virus RNA%Fluorescence quantitative PCR%Antibody of HCV
目的：探讨慢性丙型肝炎患者外周血中HCV抗体与HCV RNA检测的相关性，为临床诊断提供依据。方法收集95例疑似慢性丙型肝炎患者血清，采用荧光定量逆转录聚合酶链反应(FQ-RT-PCR)进行丙型肝炎病毒检测及化学发光法检测HCV抗体。结果 HCV RNA阳性率为75.8%（72/95）；HCV抗体阳性率为71.6%（68/95），HCV抗体阳性率与HCV RNA含量呈正相关（r=0.941，P＜0.01）。结论 HCV抗体和HCVRNA的联合检测，对于丙型肝炎的临床诊断具有重要意义。
目的：探討慢性丙型肝炎患者外週血中HCV抗體與HCV RNA檢測的相關性，為臨床診斷提供依據。方法收集95例疑似慢性丙型肝炎患者血清，採用熒光定量逆轉錄聚閤酶鏈反應(FQ-RT-PCR)進行丙型肝炎病毒檢測及化學髮光法檢測HCV抗體。結果 HCV RNA暘性率為75.8%（72/95）；HCV抗體暘性率為71.6%（68/95），HCV抗體暘性率與HCV RNA含量呈正相關（r=0.941，P＜0.01）。結論 HCV抗體和HCVRNA的聯閤檢測，對于丙型肝炎的臨床診斷具有重要意義。
목적：탐토만성병형간염환자외주혈중HCV항체여HCV RNA검측적상관성，위림상진단제공의거。방법수집95례의사만성병형간염환자혈청，채용형광정량역전록취합매련반응(FQ-RT-PCR)진행병형간염병독검측급화학발광법검측HCV항체。결과 HCV RNA양성솔위75.8%（72/95）；HCV항체양성솔위71.6%（68/95），HCV항체양성솔여HCV RNA함량정정상관（r=0.941，P＜0.01）。결론 HCV항체화HCVRNA적연합검측，대우병형간염적림상진단구유중요의의。
Objective To study the correlation between HCV RNA quantitation and anti-HCV level in the chronic hepatitis C patients. Methods HCV RNA quantitation of 95 in the chronic hepatitis C patients were detected by auantitafed fluorescence quantitative reverse transcription polymerase chain reaction(FQ-RT-PCR) and anti-HCV level were detected by chemiluminescence immunoassay ELISA. Results There was positive correlation (r =0.883,P<0.01) between anti-HCV and HCV RNA in the chronic hepatitis C patients.Conclusion Simultaneously testing the quantitation of HCV RNA and Anti-HCV is helpful for the early diagnosis and treatment of Hepatitis C infenction.
