中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
11期
22-23
,共2页
硝普钠%多巴胺%呋塞米%顽固性心衰%疗效观察
硝普鈉%多巴胺%呋塞米%頑固性心衰%療效觀察
초보납%다파알%부새미%완고성심쇠%료효관찰
Sodium nitroprusside%Dopamine%Furosemide%Refractory heart failure%Curative effect observation
目的：探讨硝普钠与多巴胺和呋塞米合用治疗顽固性心衰的疗效。方法：收治顽固性心力衰竭患者86例，分为观察组与对照组，对照组使用利尿药、血管紧张素转换酶抑制剂、洋地黄强心类药进行治疗；治疗组在对照组治疗方案的基础上，再使用10～20mg多巴胺、25mg硝普钠、35ml 0.9%的氯化钠注射液通过静脉泵入，以2ml/小时的频率进行，5～7天1个疗程，对两组的治疗效果进行对比与分析。结果：治疗组的治疗有效率明显高于对照组，存在较大差异，有统计学意义(P＜0.05)，且两组均未出现不良反应，例如电解质紊乱、洋地黄中毒等。结论：硝普钠与多巴胺和呋塞米合用治疗顽固性心力衰竭患者，不仅能够扩张患者的血管，有效降低了外周阻力，而且还能够提高患者心肌的收缩力和心输出量，有效减少了血容量，降低患者心脏的前负荷，3种药物在顽固性心力衰竭患者治疗过程中属于相辅相成的关系，有效提高了顽固性心力衰竭患者的治疗效果，具有非常重要的意义。
目的：探討硝普鈉與多巴胺和呋塞米閤用治療頑固性心衰的療效。方法：收治頑固性心力衰竭患者86例，分為觀察組與對照組，對照組使用利尿藥、血管緊張素轉換酶抑製劑、洋地黃彊心類藥進行治療；治療組在對照組治療方案的基礎上，再使用10～20mg多巴胺、25mg硝普鈉、35ml 0.9%的氯化鈉註射液通過靜脈泵入，以2ml/小時的頻率進行，5～7天1箇療程，對兩組的治療效果進行對比與分析。結果：治療組的治療有效率明顯高于對照組，存在較大差異，有統計學意義(P＜0.05)，且兩組均未齣現不良反應，例如電解質紊亂、洋地黃中毒等。結論：硝普鈉與多巴胺和呋塞米閤用治療頑固性心力衰竭患者，不僅能夠擴張患者的血管，有效降低瞭外週阻力，而且還能夠提高患者心肌的收縮力和心輸齣量，有效減少瞭血容量，降低患者心髒的前負荷，3種藥物在頑固性心力衰竭患者治療過程中屬于相輔相成的關繫，有效提高瞭頑固性心力衰竭患者的治療效果，具有非常重要的意義。
목적：탐토초보납여다파알화부새미합용치료완고성심쇠적료효。방법：수치완고성심력쇠갈환자86례，분위관찰조여대조조，대조조사용이뇨약、혈관긴장소전환매억제제、양지황강심류약진행치료；치료조재대조조치료방안적기출상，재사용10～20mg다파알、25mg초보납、35ml 0.9%적록화납주사액통과정맥빙입，이2ml/소시적빈솔진행，5～7천1개료정，대량조적치료효과진행대비여분석。결과：치료조적치료유효솔명현고우대조조，존재교대차이，유통계학의의(P＜0.05)，차량조균미출현불량반응，례여전해질문란、양지황중독등。결론：초보납여다파알화부새미합용치료완고성심력쇠갈환자，불부능구확장환자적혈관，유효강저료외주조력，이차환능구제고환자심기적수축력화심수출량，유효감소료혈용량，강저환자심장적전부하，3충약물재완고성심력쇠갈환자치료과정중속우상보상성적관계，유효제고료완고성심력쇠갈환자적치료효과，구유비상중요적의의。
Objective:To explore the curative effect of sodium nitroprusside combined with dopamine and furosemide in the treatment of refractory heart failure.Methods:86 patients with refractory heart failure were selected,they were divided into the observation group and the control group.The control group was treated with diuretics,angiotensin converting enzyme inhibitors and digitalis drugs.The treatment group added 10~20mg dopamine,25mg sodium nitroprusside and 35ml 0.9%physiological saline by venous pump with the frequency of 2ml/hours.5~7 days were 1 treatment course.The treatment effect of the two groups were compared and analyzed.Results:In the treatment group,the effective rate was significantly higher than the control group,the difference was statistically significant(P<0.05);The two groups were no adverse effects,such as electrolyte disorder,digitalis poisoning and so on.Conclusion:The combination of sodium nitroprusside with dopamine and furosemide in the treatment of refractory heart failure can not only expand the patient's blood vessels and reduce the peripheral resistance,but also can improve the contractility and cardiac output in patients and effectively reduce the blood volume and the load of the heart.The three drugs in the treatment of refractory heart failure are complementary relationship.They effectively enhance the treatment effect of patients with refractory heart failure,and has a very important significance.
