CAJ | 학술논문

发酵效价的高低是衡量发酵生产水平的标准，通过添加适宜的前体物质可提高阿维菌素的发酵效价。本试验选择与阿维菌素结构有部分相同的小分子物质丙醇、丙酸钠、乙酸钠作为前体物质，参与到阿维菌素的生物合成反应中，待发酵周期结束后测定发酵液的发酵效价。试验研究结果表明，将前体物质直接滴加到发酵液中比将前体物质添加到培养基中，能显著提高阿维菌素发酵效价。
발효효개적고저시형량발효생산수평적표준，통과첨가괄의적전체물질가제고아유균소적발효효개。본시험선택여아유균소결구유부분상동적소분자물질병순、병산납、을산납작위전체물질，삼여도아유균소적생물합성반응중，대발효주기결속후측정발효액적발효효개。시험연구결과표명，장전체물질직접적가도발효액중비장전체물질첨가도배양기중，능현저제고아유균소발효효개。
The fermentation titer level is a measure of fermentation production standards, by adding precursor substances suitable can improve the fermentation titer of avermectin. The test selection with abamectin structure are part of the same small molecule alcohol, sodium propionate, sodium acetate as precursors, involved in the biosynthesis of Avermectin Fermentation reaction, determination of titer of fermentation liquid after the end of the fermentation period. Experimental results show that, the precursor material directly dripped into the fermentation liquor ratio will add the precursors to the culture medium, can significantly improve the Avermectin Fermentation titer.