CAJ | 학술논문

目的探讨首发抑郁症患者的脂代谢情况。方法对200例首发抑郁症患者及100名健康的人先进行体脂参数的测量，然后检测其空腹血浆甘油三脂、胆固醇的浓度。结果体脂参数，抑郁症组与对照组两组比较无统计学差异（P＞0.05）；抑郁症组甘油三脂（TG）值明显高于对照组，两组比较有显著性差异(P<0.01)；而高密度脂蛋白（HDL—ch）、载脂蛋白A1（ApoA1）值抑郁症组明显低于对照组，两组比较有显著性差异(P<0.01)，血浆总胆固醇(TC)、低密度脂蛋白胆固醇(LDL—ch)和载脂蛋白B(ApoB)值两组间均无统计学差异(P＞0.05)。结论首发抑郁症患者存在一定的脂代谢异常，临床医师应该对抑郁症患者的血脂进行随访监测，以便早期发现、治疗脂代谢性疾病。
목적탐토수발억욱증환자적지대사정황。방법대200례수발억욱증환자급100명건강적인선진행체지삼수적측량，연후검측기공복혈장감유삼지、담고순적농도。결과체지삼수，억욱증조여대조조량조비교무통계학차이（P＞0.05）；억욱증조감유삼지（TG）치명현고우대조조，량조비교유현저성차이(P<0.01)；이고밀도지단백（HDL—ch）、재지단백A1（ApoA1）치억욱증조명현저우대조조，량조비교유현저성차이(P<0.01)，혈장총담고순(TC)、저밀도지단백담고순(LDL—ch)화재지단백B(ApoB)치량조간균무통계학차이(P＞0.05)。결론수발억욱증환자존재일정적지대사이상，림상의사응해대억욱증환자적혈지진행수방감측，이편조기발현、치료지대사성질병。
Objective: To investigate lipid metabolism of the first-episode patients with depression. Methods: Simple measurement of fatness parameters of 200 firs-epi-sode depressed patients and 100 healthy people,then to detect levels of empty blood plasma triglyeride(TG) and cholesterol. Result: There is no statistically significant differences in fatness parameters; empty stomach blood plasma TG levels of depressi-on group are significantly higher than the control group, the difference was statistically (P<0.01);High density lipoprotein cholesterol(HDL—ch), ApoA1 are significantly lower than the control group, the differences are statistically significant(P<0.01); there are no significant differences between the two groups in levels of blood plasma total cholesterol (TC) and low density lipoprotein cholesterol (LDL—ch) and ApoB (P>0.05). Conclusion: First-ever depressed patients are abnormal in lipid metabolism ,clinician should bring along blood lip in order to early discovery and treat disease of lipid metabolism.